Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.42 |
| ▸ | NOS1 | P29475 | 2/20 | 0.42 |
| ▸ | NOS2 | P35228 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1424464 | 0.83 | TSHR (0.35) | NOS3NOS1NOS2TSHRLMNA | |
| SCHEMBL19705414 | 0.83 | TSHR (0.53) | NOS3NOS1NOS2GABRA1GABRB2 | |
| SCHEMBL29324813 | 0.81 | MAOA (0.43) | NOS3NOS1NOS2GABRA1GABRB2 | |
| SCHEMBL15617285 | 0.81 | GABRA1 (0.40) | NOS3NOS1NOS2GABRA1GABRB2 | |
| SCHEMBL27993344 | 0.79 | MAOA (0.38) | NOS3NOS1NOS2LMNACYP3A4 | |
| SCHEMBL9793625 | 0.78 | S100A4 (0.41) | TSHRLMNAHPGDBLMS100A4 | |
| SCHEMBL27993112 | 0.78 | MAOA (0.41) | NOS3NOS1NOS2LMNACYP3A4 | |
| SCHEMBL11080622 | 0.78 | NOS3 (0.36) | NOS3NOS1NOS2LMNAS100A4 | |
| SCHEMBL4808650 | 0.77 | GABRA1 (0.48) | GABRA1GABRB2GABRG2GABRB3TSHR | |
| SCHEMBL944019 | 0.77 | GABRA1 (0.48) | NOS3NOS1NOS2GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11591335-B2 | Bicyclic pesticidal compounds | BASF SE (DE) | 2023-02-28 | — | — | US | disclosed |
| US-11570992-B2 | Bicyclic compounds | BASF SE (DE) | 2023-02-07 | — | — | US | disclosed |
| WO-2021086044-A1 | NOVEL COMPOUND FOR CROP PROTECTANT | 주식회사 엘지화학 | 2021-05-06 | — | — | WO | disclosed |
| US-20200165255-A1 | Bicyclic Pesticidal Compounds | BASF SE (DE) | 2020-05-28 | — | — | US | disclosed |
| EP-3429355-B1 | SUBSTITUTED SULFONYLAMIDE FOR COMBATING ANIMAL PESTS | BAYER CROPSCIENCE AG (DE) | 2020-02-05 | — | — | EP | disclosed |
| EP-3152216-B1 | BICYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2019-07-24 | — | — | EP | disclosed |
| US-10294243-B2 | Bicyclic compounds as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-05-21 | — | — | US | disclosed |
| US-20190104738-A1 | BICYCLIC COMPOUNDS | BASF CHEMICALS INDIA PVT. LTD. (IN) | 2019-04-11 | — | — | US | disclosed |
| EP-3227302-B1 | BICYCLIC COMPOUNDS AS PEST CONTROLLERS | BAYER CROPSCIENCE AG (DE) | 2018-07-11 | — | — | EP | disclosed |
| US-20170355714-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-12-14 | — | — | US | disclosed |
| WO-2017157735-A1 | SUBSTITUTED SULFONYL AMIDES FOR CONTROLLING ANIMAL PESTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-09-21 | — | — | WO | disclosed |
| US-20170101422-A1 | Bicyclic compounds as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-04-13 | — | — | US | disclosed |
| US-20170101422-A1 | Bicyclic compounds as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-04-13 | — | — | US | disclosed |
| US-8835423-B2 | Azepine inhibitors of janus kinases | INCYTE CORPORATION (US) | 2014-09-16 | — | — | US | disclosed |
| US-20140031344-A1 | AZEPINE INHIBITORS OF JANUS KINASES | INCYTE CORPORATION (US) | 2014-01-30 | — | — | US | disclosed |
| US-8563541-B2 | Azepine inhibitors of Janus kinases | INCYTE CORPORATION (US) | 2013-10-22 | — | — | US | disclosed |
| US-20120329782-A1 | AZEPINE INHIBITORS OF JANUS KINASES | INCYTE CORPORATION (US) | 2012-12-27 | — | — | US | disclosed |
| US-20120329782-A1 | AZEPINE INHIBITORS OF JANUS KINASES | INCYTE CORPORATION (US) | 2012-12-27 | — | — | US | disclosed |
| US-20090197869-A1 | AZEPINE INHIBITORS OF JANUS KINASES | INCYTE CORPORATION, A DELAWARE CORPORATION | 2009-08-06 | — | — | US | disclosed |
| US-20070149506-A1 | Azepine inhibitors of Janus kinases | INCYTE CORPORATION | 2007-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200165255-A1 | Bicyclic Pesticidal Compounds | DDT, ACHE, CYCS | NOS3 1237/4885NOS1 1999/4885NOS2 1938/4885 |
| US-20120329782-A1 | AZEPINE INHIBITORS OF JANUS KINASES | JAK1, JAK3, JAK2 | NOS3 1425/4885NOS1 1206/4885NOS2 1416/4885 |
| US-11591335-B2 | Bicyclic pesticidal compounds | DDT, ACHE, CYCS | NOS3 1237/4885NOS1 1999/4885NOS2 1938/4885 |
| US-20190104738-A1 | BICYCLIC COMPOUNDS | CYP1B1, CYCS, CYP11B2 | NOS3 2441/4885NOS1 2622/4885NOS2 2558/4885 |
| US-11570992-B2 | Bicyclic compounds | CYP1B1, CYCS, CYP11B2 | NOS3 2441/4885NOS1 2622/4885NOS2 2558/4885 |
| US-10294243-B2 | Bicyclic compounds as pesticides | DDT, BCHE, CYCS | NOS3 3222/4885NOS1 4089/4885NOS2 3988/4885 |
| US-20170355714-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | DDT, BCHE, BAK1 | NOS3 3961/4885NOS1 4395/4885NOS2 4267/4885 |
| US-20170101422-A1 | Bicyclic compounds as pesticides | DDT, BCHE, CYCS | NOS3 3222/4885NOS1 4089/4885NOS2 3988/4885 |
| US-20090197869-A1 | AZEPINE INHIBITORS OF JANUS KINASES | JAK1, JAK3, JAK2 | NOS3 1425/4885NOS1 1206/4885NOS2 1416/4885 |
| US-20070149506-A1 | Azepine inhibitors of Janus kinases | JAK1, JAK3, JAK2 | NOS3 1425/4885NOS1 1206/4885NOS2 1416/4885 |
| US-20140031344-A1 | AZEPINE INHIBITORS OF JANUS KINASES | JAK1, JAK3, JAK2 | NOS3 1425/4885NOS1 1206/4885NOS2 1416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.