Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 4/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29491165 | 1.00 | SPR (0.38) | SPRGPR119AAK1PDE10AKDM4D | |
| SCHEMBL22650571 | 0.87 | CCR5 (0.39) | GPR119ROCK2 | |
| SCHEMBL30700827 | 0.86 | AAK1 (0.43) | GPR119AAK1PDE10AKDM4DJAK2 | |
| SCHEMBL20037702 | 0.86 | AAK1 (0.43) | GPR119AAK1PDE10AKDM4DJAK2 | |
| SCHEMBL22650573 | 0.84 | LIPE (0.35) | GPR119HSD11B1ROCK2 | |
| SCHEMBL22650368 | 0.81 | ALOX5AP (0.37) | PIK3CA | |
| SCHEMBL29462389 | 0.81 | ALOX5AP (0.37) | PIK3CA | |
| SCHEMBL23104497 | 0.81 | RET (0.45) | SPRAAK1PDE10AKDM4DJAK2 | |
| SCHEMBL23104405 | 0.81 | RET (0.45) | SPRAAK1PDE10AKDM4DJAK2 | |
| SCHEMBL29736351 | 0.81 | RET (0.45) | SPRAAK1PDE10AKDM4DJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120040446-A | CDK inhibitors | 基因泰克公司 | 2025-05-27 | — | — | CN | disclosed |
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |