Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.33 |
| ▸ | FEN1 | P39748 | 2/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | GCK | P35557 | 1/20 | 0.32 |
| ▸ | GCKR | Q14397 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22650571 | 0.89 | CCR5 (0.39) | LIPEROCK2GPR119SCN9ASCN10A | |
| SCHEMBL22650570 | 0.87 | LIPE (0.37) | LIPEROCK2GPR119HSD11B1 | |
| SCHEMBL29491165 | 0.84 | SPR (0.38) | ROCK2GPR119HSD11B1 | |
| SCHEMBL22650412 | 0.84 | SPR (0.38) | ROCK2GPR119HSD11B1 | |
| SCHEMBL22650566 | 0.81 | DPP4 (0.33) | DPP4ALOX5APFEN1GCKGCKR | |
| SCHEMBL22650368 | 0.74 | ALOX5AP (0.37) | ALOX5APFEN1GCKR | |
| SCHEMBL29462389 | 0.74 | ALOX5AP (0.37) | ALOX5APFEN1GCKR | |
| SCHEMBL22650562 | 0.74 | PIK3CA (0.35) | — | |
| SCHEMBL22650910 | 0.73 | DRD3 (0.35) | ROCK2 | |
| SCHEMBL22650572 | 0.73 | CCR5 (0.38) | LIPEDPP4GPR119MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |