Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | BCR | P11274 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 6/20 | 0.39 |
| ▸ | CDK1 | P06493 | 3/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.39 |
| ▸ | CCND1 | P24385 | 2/20 | 0.39 |
| ▸ | SYK | P43405 | 4/20 | 0.38 |
| ▸ | CDK2 | P24941 | 5/20 | 0.38 |
| ▸ | CDK9 | P50750 | 4/20 | 0.38 |
| ▸ | GSK3B | P49841 | 4/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.38 |
| ▸ | CDK8 | P49336 | 3/20 | 0.38 |
| ▸ | CCND3 | P30281 | 3/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.38 |
| ▸ | CCNK | O75909 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22650918 | 0.79 | DKK1 (0.57) | CDK1CCNB1CDK2CDK9GSK3B | |
| SCHEMBL22650923 | 0.79 | MAPK8 (0.54) | CDK4CDK1CCNB1CCND1CDK2 | |
| SCHEMBL22650920 | 0.79 | CDK2 (0.54) | ABL1PDGFRBBCRPDGFRACDK4 | |
| SCHEMBL22650919 | 0.78 | CDK2 (0.54) | PRKCACDK4CDK1CCNB1CCND1 | |
| SCHEMBL22650921 | 0.78 | MTOR (0.49) | ABL1BCRCDK4CDK1CCNB1 | |
| SCHEMBL22650796 | 0.76 | CDK2 (0.44) | CDK4CDK1CCNB1CCND1CDK2 | |
| SCHEMBL22650422 | 0.76 | CDK1 (0.41) | PRKCAABL1PDGFRBBCRSRC | |
| SCHEMBL22650849 | 0.76 | CDK1 (0.47) | CDK1CDK2JAK2JAK3MTOR | |
| SCHEMBL22650927 | 0.75 | CDK2 (0.52) | CDK4CDK1CCNB1CCND1CDK2 | |
| SCHEMBL22650365 | 0.71 | DYRK1A (0.36) | PRKCACDK4CDK1CCNB1CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |