Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 3/20 | 0.33 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.33 |
| ▸ | WNT1 | P04628 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22650942 | 0.89 | CDK4 (0.34) | F10DEGS1WNT1GSK3BDYRK1A | |
| SCHEMBL24483448 | 0.83 | WNT3A (0.50) | WNT3ANPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL22650505 | 0.80 | F10 (0.38) | SLC6A2CACNA2D1F10CDK4CCND1 | |
| SCHEMBL22544380 | 0.76 | FGFR3 (0.44) | NPC1RAB9ACDK4CCND1CDK6 | |
| SCHEMBL22650899 | 0.73 | USP30 (0.34) | CDK4CCND1CDK2 | |
| SCHEMBL22650900 | 0.73 | USP30 (0.34) | CDK4CCND1CDK2 | |
| SCHEMBL22650832 | 0.72 | TSHR (0.38) | CDK4 | |
| SCHEMBL22650833 | 0.70 | TSHR (0.36) | CDK4 | |
| SCHEMBL29557854 | 0.70 | WNT3A (0.52) | WNT3ANPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL24483273 | 0.68 | CHRNB2 (0.49) | CDK4CCND1CDK6CCNA2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |