Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 4/20 | 0.35 |
| ▸ | CCND1 | P24385 | 3/20 | 0.35 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CCND3 | P30281 | 1/20 | 0.35 |
| ▸ | CDK7 | P50613 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | CCNH | P51946 | 1/20 | 0.35 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24483273 | 0.82 | CHRNB2 (0.49) | CDK4CCND1CDK6CCNT1CCND3 | |
| SCHEMBL22650606 | 0.80 | WNT3A (0.39) | F10CDK4CCND1CDK6CACNA2D1 | |
| SCHEMBL22650942 | 0.78 | CDK4 (0.34) | F10CDK4CCND1CDK6CCND3 | |
| SCHEMBL18291654 | 0.75 | PIM1 (0.43) | F10HTR6CACNA2D1SLC6A2PIM1 | |
| SCHEMBL22650899 | 0.75 | USP30 (0.34) | CDK4CCND1 | |
| SCHEMBL22650900 | 0.75 | USP30 (0.34) | CDK4CCND1 | |
| SCHEMBL22650832 | 0.74 | TSHR (0.38) | CDK4 | |
| SCHEMBL5158426 | 0.73 | HTR6 (0.43) | F10HTR6CACNA2D1SLC6A2PIM1 | |
| SCHEMBL20037996 | 0.72 | HTR6 (0.42) | F10HTR6CACNA2D1SLC6A2PIM1 | |
| SCHEMBL22650833 | 0.72 | TSHR (0.36) | CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |