Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 9/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22650833 | 0.84 | TSHR (0.36) | TSHRMAPK1CDK4CDK1 | |
| SCHEMBL22650900 | 0.78 | USP30 (0.34) | CDK4CDK1 | |
| SCHEMBL22650899 | 0.78 | USP30 (0.34) | CDK4CDK1 | |
| SCHEMBL22650505 | 0.74 | F10 (0.38) | CDK4 | |
| SCHEMBL22650606 | 0.72 | WNT3A (0.39) | CDK4 | |
| SCHEMBL22650942 | 0.70 | CDK4 (0.34) | CDK4CDK1 | |
| SCHEMBL21580294 | 0.69 | DPP4 (0.54) | CYP3A4CYP2C19 | |
| SCHEMBL24483273 | 0.68 | CHRNB2 (0.49) | CDK4CDK1 | |
| SCHEMBL20901706 | 0.66 | TSHR (0.55) | TSHRMAPK1LMNAKMT2AMEN1 | |
| SCHEMBL20901666 | 0.66 | TSHR (0.55) | TSHRMAPK1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |