Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 17/20 | 0.36 |
| ▸ | CDK1 | P06493 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22650900 | 0.89 | USP30 (0.34) | CDK4CDK1 | |
| SCHEMBL22650899 | 0.89 | USP30 (0.34) | CDK4CDK1 | |
| SCHEMBL22650832 | 0.84 | TSHR (0.38) | TSHRMAPK1CDK4CDK1 | |
| SCHEMBL22650505 | 0.72 | F10 (0.38) | CDK4 | |
| SCHEMBL22650606 | 0.70 | WNT3A (0.39) | CDK4 | |
| SCHEMBL22650942 | 0.69 | CDK4 (0.34) | CDK4CDK1 | |
| SCHEMBL24483273 | 0.66 | CHRNB2 (0.49) | CDK4CDK1 | |
| SCHEMBL24483448 | 0.65 | WNT3A (0.50) | CDK4CDK1 | |
| SCHEMBL24483274 | 0.64 | WNT3A (0.57) | TSHR | |
| SCHEMBL22650368 | 0.64 | ALOX5AP (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |