Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | CCND3 | P30281 | 1/20 | 0.32 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22650618 | 0.93 | TTK (0.33) | EGFRCCND3CDK6 | |
| SCHEMBL22650777 | 0.90 | ACVR1 (0.35) | EGFRCDK6 | |
| SCHEMBL22650576 | 0.90 | CDK6 (0.38) | CCND3CDK6 | |
| SCHEMBL22650541 | 0.82 | EGFR (0.36) | EGFR | |
| SCHEMBL22650532 | 0.82 | EGFR (0.36) | EGFRCCND3CDK6 | |
| SCHEMBL22650513 | 0.80 | CDK4 (0.36) | CCND3CDK6 | |
| SCHEMBL22650715 | 0.77 | CDK6 (0.35) | EGFRCCND3CDK6 | |
| SCHEMBL22650496 | 0.76 | EGFR (0.38) | EGFRCCND3CDK6 | |
| SCHEMBL22650579 | 0.76 | CDK4 (0.48) | CCND3CDK6 | |
| SCHEMBL22650875 | 0.76 | TYK2 (0.44) | CCND3CDK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |