Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 9/20 | 0.38 |
| ▸ | JAK3 | P52333 | 5/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 6/20 | 0.36 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.36 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 4/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22650701 | 0.91 | JAK2 (0.38) | JAK2JAK3MAPK8MAPK10CDK1 | |
| SCHEMBL22650604 | 0.90 | JAK2 (0.37) | JAK2JAK3MAPK8MAPK10CDK1 | |
| SCHEMBL22650707 | 0.85 | JAK2 (0.39) | JAK2JAK3CDK1CDK4CCNB1 | |
| SCHEMBL22650423 | 0.82 | JAK2 (0.37) | JAK2JAK3MAPK8MAPK10CDK1 | |
| SCHEMBL22650940 | 0.79 | BTK (0.38) | CDK1CDK4CCNB1CCND1CDK9 | |
| SCHEMBL22650450 | 0.78 | CDK4 (0.41) | CDK1CDK4CCNB1CCND1CDK9 | |
| SCHEMBL22650709 | 0.76 | JAK2 (0.39) | JAK2JAK3CDK1CDK4CCNB1 | |
| SCHEMBL22650427 | 0.76 | EGFR (0.36) | JAK2JAK3CDK1CDK4CDK9 | |
| SCHEMBL22650419 | 0.75 | JAK2 (0.38) | JAK2JAK3CDK1CDK4CCNB1 | |
| SCHEMBL22650599 | 0.73 | DKK1 (0.43) | MAPK8MAPK10CDK1CDK4CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |