SCHEMBL2265125

SCHEMBL2265125

c1ccc2c(c1)ccn2-c1ncco1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC7 O00311 2/20 0.51
CDK2 P24941 2/20 0.51
ROCK1 Q13464 1/20 0.51
BIRC5 O15392 1/20 0.42
MKNK1 Q9BUB5 4/20 0.41
PRKD3 O94806 1/20 0.41
PRKCG P05129 1/20 0.41
PRKCB P05771 1/20 0.41
PRKCA P17252 1/20 0.41
PRKACA P17612 1/20 0.41
PRKACG P22612 1/20 0.41
PRKACB P22694 1/20 0.41
PRKCH P24723 1/20 0.41
PRKCI P41743 1/20 0.41
PRKCE Q02156 1/20 0.41
PRKCQ Q04759 1/20 0.41
PRKCZ Q05513 1/20 0.41
PRKCD Q05655 1/20 0.41
PRKD1 Q15139 1/20 0.41
MKNK2 Q9HBH9 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2590108 0.72 RPS6KA5 (0.60) CDC7CDK2ROCK1BIRC5MKNK1
SCHEMBL29388240 0.72 RPS6KA5 (0.60) CDC7CDK2ROCK1BIRC5MKNK1
SCHEMBL6797544 0.71 LRRK2 (0.46) MKNK1MKNK2MAPK8MAPK9MAPK10
SCHEMBL29740051 0.70 ADORA3 (0.41) HTR3ACA12BRD4CA9
SCHEMBL21608541 0.70 RXFP1 (0.33) ROCK1MAPTHTR3A
SCHEMBL4867053 0.69 L3MBTL1 (0.42) MKNK1MKNK2MAPTSLC6A2HTR3A
SCHEMBL11229668 0.69 BIRC5 (0.46) CDC7CDK2ROCK1BIRC5PRKD3
SCHEMBL29388549 0.69 CDC7 (0.60) CDC7CDK2ROCK1BIRC5MKNK1
SCHEMBL524138 0.69 CDC7 (0.60) CDC7CDK2ROCK1BIRC5MKNK1
SCHEMBL31107087 0.69 CDC7 (0.60) CDC7CDK2ROCK1BIRC5MKNK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2748304-A2 ISOLATED BACTERIAL STRAIN OF THE GENUS BURKHOLDERIA AND PESTICIDAL METABOLITES THEREFROM-FORMULATIONS AND USES Marrone Bio Innovations, Inc. (US) 2014-07-02 EP claimed
WO-2014088697-A2 PLANT GLUTAMINE SYNTHETASE INHIBITORS AND METHODS FOR THEIR IDENTIFICATION MARRONE BIO INNOVATIONS, INC. (US) 2014-06-12 WO claimed
US-20140113816-A1 PLANT GLUTAMINE SYNTHETASE INHIBITORS AND METHODS FOR THEIR IDENTIFICATION PRO FARM GROUP, INC. 2014-04-24 US claimed
CN-103261398-A Isolated bacterial strains of the genus burkholderia and pesticide metabolites thereof MARRONE BIO INNOVATIONS INC 2013-08-21 CN claimed
WO-2013032693-A2 ISOLATED BACTERIAL STRAIN OF THE GENUS BURKHOLDERIA AND PESTICIDAL METABOLITES THEREFROM-FORMULATIONS AND USES MARRONE BIO INNOVATIONS, INC. (US) 2013-03-07 WO claimed
EP-2539432-A2 ISOLATED BACTERIAL STRAIN OF THE GENUS BURKHOLDERIA AND PESTICIDAL METABOLITES THEREFROM Marrone Bio Innovations, Inc. (US) 2013-01-02 EP claimed
WO-2011106491-A2 ISOLATED BACTERIAL STRAIN OF THE GENUS BURKHOLDERIA AND PESTICIDAL METABOLITES THEREFROM MARRONE BIO INNOVATIONS, INC. (US) 2011-09-01 WO claimed
US-20110207604-A1 ISOLATED BACTERIAL STRAIN OF THE GENUS BURKHOLDERIA AND PESTICIDAL METABOLITES THEREFROM MARRONE BIO INNOVATIONS (US) 2011-08-25 US claimed
US-12075785-B2 Isolated bacterial strain of the genus Burkholderia and pesticidal metabolites therefrom PRO FARM GROUP, INC. (US) 2024-09-03 US disclosed
US-11793201-B2 Isolated bacterial strain of the genus Burkholderia and pesticidal metabolites therefrom PRO FARM GROUP, INC. (US) 2023-10-24 US disclosed
US-20220304312-A1 Isolated Bacterial Strain of the Genus Burkholderia and Pesticidal Metabolites Therefrom MARRONE BIO INNOVATIONS, INC. (US) 2022-09-29 US disclosed
US-11382331-B2 Isolated bacterial strain of the genus Burkholderia and pesticidal metabolites therefrom MARRONE BIO INNOVATIONS, INC. (US) 2022-07-12 US disclosed
US-20200288715-A1 Isolated Bacterial Strain of the Genus Burkholderia and Pesticidal Metabolites Therefrom MARRONE BIO INNOVATIONS, INC. (US) 2020-09-17 US disclosed
US-20190313645-A1 Isolated Bacterial Strain of the Genus Burkholderia and Pesticidal Metabolites Therefrom MARRONE BIO INNOVATIONS, INC. (US) 2019-10-17 US disclosed
CN-1609101-B Organometallic complex and light-emitting element containing the same SEMICONDUCTOR ENERGY LAB 2010-05-26 CN disclosed
US-7314769-B2 Organometallic complex and light-emitting element containing the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-01-01 US disclosed
US-6998492-B2 Organometallic complex and light-emitting element containing the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2006-02-14 US disclosed
CN-1609101-A Organometallic complex and light-emitting element containing the same SEMICONDUCTOR ENERGY LAB (JP) 2005-04-27 CN disclosed
US-20050033054-A1 Organometallic complex and light-emitting element containing the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2005-02-10 US disclosed
US-20040230061-A1 Organometallic complex and light-emitting element containing the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2004-11-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12075785-B2 Isolated bacterial strain of the genus Burkholderia and pesticidal metabolites therefrom NOTUM, WASF2, WEE1 CDC7 2026/4885CDK2 3261/4885ROCK1 756/4885
US-11382331-B2 Isolated bacterial strain of the genus Burkholderia and pesticidal metabolites therefrom NOTUM, WASF2, WEE1 CDC7 2026/4885CDK2 3261/4885ROCK1 756/4885
US-20050033054-A1 Organometallic complex and light-emitting element containing the same BCKDK, CCNK, CDK20 CDC7 239/4885CDK2 34/4885ROCK1 2919/4885
US-20200288715-A1 Isolated Bacterial Strain of the Genus Burkholderia and Pesticidal Metabolites Therefrom NOTUM, WASF2, WEE1 CDC7 2026/4885CDK2 3261/4885ROCK1 756/4885
US-20190313645-A1 Isolated Bacterial Strain of the Genus Burkholderia and Pesticidal Metabolites Therefrom NOTUM, WASF2, WEE1 CDC7 2026/4885CDK2 3261/4885ROCK1 756/4885
US-20110207604-A1 ISOLATED BACTERIAL STRAIN OF THE GENUS BURKHOLDERIA AND PESTICIDAL METABOLITES THEREFROM NOTUM, WASF2, WEE1 CDC7 2026/4885CDK2 3261/4885ROCK1 756/4885
US-20140113816-A1 PLANT GLUTAMINE SYNTHETASE INHIBITORS AND METHODS FOR THEIR IDENTIFICATION GLUL, ASNS, GLS CDC7 1433/4885CDK2 1315/4885ROCK1 4040/4885
US-20220304312-A1 Isolated Bacterial Strain of the Genus Burkholderia and Pesticidal Metabolites Therefrom NOTUM, WASF2, WEE1 CDC7 2026/4885CDK2 3261/4885ROCK1 756/4885
US-11793201-B2 Isolated bacterial strain of the genus Burkholderia and pesticidal metabolites therefrom NOTUM, WASF2, WEE1 CDC7 2026/4885CDK2 3261/4885ROCK1 756/4885
US-20040230061-A1 Organometallic complex and light-emitting element containing the same NR0B1, BCKDK, NR4A1 CDC7 521/4885CDK2 76/4885ROCK1 3239/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.