SCHEMBL2266296

SCHEMBL2266296

CCCC[Si](CC)(CCCC)N(C)C

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 3/20 0.32
TSHR P16473 2/20 0.32
LMNA P02545 1/20 0.32
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2272825 0.95
SCHEMBL2267526 0.88 TSHR (0.35) DNM1TSHRLMNATHRB
SCHEMBL2271154 0.83 DNM1 (0.32) DNM1TSHRLMNATHRB
SCHEMBL20500151 0.80 DNM1 (0.39) DNM1TSHRLMNATHRB
SCHEMBL2270973 0.77
SCHEMBL2271878 0.76 LMNA (0.30) TSHRLMNA
SCHEMBL510702 0.75
SCHEMBL2102438 0.72 DNM1 (0.32) DNM1TSHRLMNATHRB
SCHEMBL28339433 0.72 ALDH1A1 (0.33) DNM1TSHRLMNATHRB
SCHEMBL11516798 0.72 DNM1 (0.30) DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed