Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 1/20 | 0.63 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.63 |
| ▸ | LOXL4 | Q96JB6 | 1/20 | 0.63 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 10/20 | 0.60 |
| ▸ | MEN1 | O00255 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | GFER | P55789 | 2/20 | 0.59 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.58 |
| ▸ | NSD2 | O96028 | 1/20 | 0.58 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | CES2 | O00748 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5928903 | 0.88 | MAPT (0.48) | LOXLOXL3LOXL4LOXL2MAPT | |
| SCHEMBL3727261 | 0.85 | LOX (0.61) | LOXLOXL3LOXL4LOXL2MAPT | |
| SCHEMBL5928736 | 0.84 | MAPT (0.49) | LOXLOXL3LOXL4LOXL2MAPT | |
| SCHEMBL22670032 | 0.83 | POLB (0.49) | LOXLOXL3LOXL4LOXL2MAPT | |
| SCHEMBL5929007 | 0.83 | MAPT (0.50) | LOXLOXL3LOXL4LOXL2MAPT | |
| SCHEMBL5928818 | 0.81 | MEN1 (0.50) | LOXLOXL3LOXL4LOXL2MAPT | |
| SCHEMBL5928768 | 0.80 | CES2 (0.59) | LOXLOXL3LOXL4LOXL2MAPT | |
| SCHEMBL5928770 | 0.79 | MAPT (0.67) | MAPTMEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL186331 | 0.79 | LOX (0.71) | LOXLOXL3LOXL4LOXL2MAPT | |
| SCHEMBL17290527 | 0.79 | CES2 (0.57) | LOXLOXL3LOXL4LOXL2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023093399-A1 | BENZOTHIAZOLE-PARENT-BASED FLUORESCENT PROBE FOR DETECTION OF PALLADIUM IONS, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 江苏科技大学 | 2023-06-01 | — | — | WO | claimed |
| WO-2023093399-A1 | BENZOTHIAZOLE-PARENT-BASED FLUORESCENT PROBE FOR DETECTION OF PALLADIUM IONS, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 江苏科技大学 | 2023-06-01 | — | — | WO | disclosed |
| WO-2023093399-A1 | BENZOTHIAZOLE-PARENT-BASED FLUORESCENT PROBE FOR DETECTION OF PALLADIUM IONS, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 江苏科技大学 | 2023-06-01 | — | — | WO | disclosed |
| CN-113912596-B | Benzothiazole matrix-based palladium ion detection fluorescent probe and preparation method and application thereof | 江苏科技大学 | 2022-12-02 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| CN-113912596-A | Benzothiazole matrix-based palladium ion detection fluorescent probe and preparation method and application thereof | 江苏科技大学 | 2022-01-11 | — | — | CN | disclosed |
| US-7887933-B2 | A layer of an electroluminescent material between first and second electrodes composed of a metal complex, preferably aluminium, of a substituted pyrazol-5-one, free of lanthanides or actinides; used to make flat panel displays | MERCK PATENT GMBH (DE) | 2011-02-15 | — | — | US | disclosed |
| EP-1666537-B1 | Colorant for ocular lenses and material for colored ocular lenses using the colorant | NIDEK KK (JP) | 2011-01-26 | — | — | EP | disclosed |
| US-7232896-B2 | Colorant for ocular lenses and material for colored ocular lenses using the colorant | NIDEK CO., LTD. (JP) | 2007-06-19 | — | — | US | disclosed |
| US-7232896-B2 | Colorant for ocular lenses and material for colored ocular lenses using the colorant | NIDEK CO., LTD. (JP) | 2007-06-19 | — | — | US | disclosed |
| EP-1043365-B1 | Polymerizable 1,2-dipyrazolylethenes as dyes for ophthalmic plastic lenses | HOYA HEALTHCARE CORP (JP) | 2006-10-18 | — | — | EP | disclosed |
| US-20060229324-A1 | Quinazolin-4-one derivatives | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2006-10-12 | — | — | US | disclosed |
| CN-1188399-C | New pyrazolone compound and eye plastic lens made therefrom | HOYA HEALTHCARE CORP (JP) | 2005-02-09 | — | — | CN | disclosed |
| US-6310215-B1 | EXCELLENT COPOLYMERIZABILITY AND UNDERGO NO ELUTION IN AN ORGANIC SOLVENT | HOYA HEALTHCARE CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| CN-1290699-A | New pyrazolone compound and eye plastic lens made therefrom | HOYA HEALTHCARE CORP (JP) | 2001-04-11 | — | — | CN | disclosed |
| EP-1043365-A1 | Polymerizable 1,2-dipyrazolylethenes as dyes for ophthalmic plastic lenses | Hoya Healthcare Corporation (JP) | 2000-10-11 | — | — | EP | disclosed |
| CN-1038138-A | The colouring method of natural or synthesizing polyamides | BASF AG (DE) | 1989-12-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060229324-A1 | Quinazolin-4-one derivatives | HPGDS, PTGS1, PTGDR | LOX 2498/4885LOXL3 2573/4885LOXL4 3196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.