Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | LOX | P28300 | 1/20 | 0.44 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.44 |
| ▸ | LOXL4 | Q96JB6 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5928903 | 0.89 | MAPT (0.48) | MAPTHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL5713339 | 0.84 | LOX (0.63) | MAPTHTTCYP2C9CYP2C19MEN1 | |
| SCHEMBL5928818 | 0.82 | MEN1 (0.50) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL22670032 | 0.81 | POLB (0.49) | MAPTHTTCYP2C9CYP2C19MEN1 | |
| SCHEMBL5928770 | 0.80 | MAPT (0.67) | MAPTHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL22678453 | 0.79 | MAPT (0.41) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL6262550 | 0.78 | MAPT (0.51) | MAPTHTTCYP2C9CYP2C19MEN1 | |
| SCHEMBL22670353 | 0.77 | ACSS2 (0.48) | MAPTHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL9525808 | 0.77 | MEN1 (0.35) | MAPTHTTCYP2C9CYP2C19MEN1 | |
| SCHEMBL5928796 | 0.76 | CES2 (0.42) | MAPTHTTCYP2C9CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060229324-A1 | Quinazolin-4-one derivatives | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2006-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060229324-A1 | Quinazolin-4-one derivatives | HPGDS, PTGS1, PTGDR | MAPT 4875/4885HTT 4273/4885CYP2C9 602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.