Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2104195 | 0.87 | SIGMAR1 (0.42) | SIGMAR1KCNH2SLC6A4SLC6A2CHRM1 | |
| SCHEMBL2100897 | 0.82 | SIGMAR1 (0.47) | SIGMAR1ALDH1A1HRH1HTR2ALMNA | |
| SCHEMBL11152840 | 0.80 | LTA4H (0.36) | SIGMAR1KCNH2 | |
| SCHEMBL704628 | 0.77 | LTA4H (0.35) | SIGMAR1HTT | |
| SCHEMBL2101606 | 0.76 | KCNH2 (0.38) | SIGMAR1KCNH2SLC6A4SLC6A2CHRM1 | |
| SCHEMBL2272064 | 0.73 | TP53 (0.35) | — | |
| SCHEMBL2266973 | 0.72 | CYP2C19 (0.39) | SIGMAR1CHRM2HTTCYP1A2 | |
| SCHEMBL2104136 | 0.72 | TAAR1 (0.43) | SIGMAR1KCNH2SLC6A4SLC6A2CHRM1 | |
| SCHEMBL2273238 | 0.71 | L3MBTL1 (0.48) | SIGMAR1KCNH2SLC6A4SLC6A2CHRM1 | |
| SCHEMBL2273389 | 0.71 | SIGMAR1 (0.49) | SIGMAR1KCNH2SLC6A4SLC6A2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404584-B2 | Method of manufacturing semiconductor device | FUJITSU LIMITED (JP) | 2013-03-26 | — | — | US | disclosed |
| US-20110207319-A1 | METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE | FUJITSU LIMITED (JP) | 2011-08-25 | — | — | US | disclosed |