SCHEMBL2273238

SCHEMBL2273238

CNCCCC[SiH](Cl)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.48
SIGMAR1 Q99720 1/20 0.47
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
HRH1 P35367 5/20 0.43
HTR2A P28223 4/20 0.43
HTR1B P28222 2/20 0.43
TAAR1 Q96RJ0 2/20 0.39
ATM Q13315 1/20 0.39
CYP3A4 P08684 3/20 0.38
TP53 P04637 2/20 0.38
CYP1A2 P05177 2/20 0.38
CYP2C9 P11712 1/20 0.38
TSHR P16473 1/20 0.38
LMNA P02545 2/20 0.37
HTR1D P28221 1/20 0.36
SLC6A4 P31645 2/20 0.36
CHRM2 P08172 2/20 0.34
CYP2D6 P10635 2/20 0.34
CHRM1 P11229 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2104019 0.86 TAAR1 (0.43) L3MBTL1SIGMAR1MEN1KMT2AHRH1
SCHEMBL2266973 0.82 CYP2C19 (0.39) SIGMAR1MEN1KMT2ACYP1A2TSHR
SCHEMBL11152840 0.79 LTA4H (0.36) SIGMAR1MEN1KMT2ATP53KCNH2
SCHEMBL704628 0.76 LTA4H (0.35) SIGMAR1MEN1KMT2ATP53TSHR
SCHEMBL2100897 0.74 SIGMAR1 (0.47) SIGMAR1HRH1HTR2AHTR1BTAAR1
SCHEMBL2102293 0.74 KDM4E (0.38) L3MBTL1SIGMAR1MEN1KMT2AHRH1
SCHEMBL2102244 0.72 HTT (0.39) SIGMAR1MEN1KMT2AHTR2AHTR1B
SCHEMBL2268231 0.71 SIGMAR1 (0.50) SIGMAR1HRH1HTR2ACYP1A2LMNA
SCHEMBL2272064 0.71 TP53 (0.35) TP53
SCHEMBL2100400 0.69 TAAR1 (0.42) L3MBTL1SIGMAR1MEN1KMT2AHRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed