Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 6/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.37 |
| ▸ | PDE2A | O00408 | 8/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 4/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22685193 | 0.84 | PDE2A (0.38) | IDO1PDE2APTGER4PTGDR | |
| SCHEMBL22685175 | 0.81 | IDO1 (0.37) | IDO1CYP2C9PDE2APTGER4PTGDR | |
| SCHEMBL22685250 | 0.77 | PTPN1 (0.40) | IDO1CYP2C9PDE2A | |
| SCHEMBL22685245 | 0.77 | MAP4K4 (0.41) | IDO1CYP2C9PDE2A | |
| SCHEMBL22685078 | 0.77 | WDR91 (0.53) | IDO1CYP2C9PDE2A | |
| SCHEMBL22685247 | 0.77 | ROCK2 (0.41) | IDO1CYP2C9PDE2A | |
| SCHEMBL22685185 | 0.76 | BTK (0.39) | IDO1CYP2C9PDE2APTGER4PTGDR | |
| SCHEMBL22685177 | 0.75 | IDO1 (0.42) | IDO1 | |
| SCHEMBL22685262 | 0.73 | WDR91 (0.40) | PDE2APTGER4PTGDRAKT1 | |
| SCHEMBL22438885 | 0.73 | IDO1 (0.52) | IDO1CYP2C9PDE2APTGER4PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |