Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 18/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22685193 | 0.89 | PDE2A (0.38) | PDE2AIDO1 | |
| SCHEMBL22685194 | 0.83 | PDE2A (0.38) | PDE2A | |
| SCHEMBL22684799 | 0.79 | IDO1 (0.39) | PDE2AIDO1 | |
| SCHEMBL22685330 | 0.76 | CXCR3 (0.42) | PDE2A | |
| SCHEMBL22685173 | 0.74 | IDO1 (0.42) | PDE2AIDO1 | |
| SCHEMBL22685179 | 0.73 | IDO1 (0.37) | PDE2AIDO1 | |
| SCHEMBL22685248 | 0.73 | PTPN1 (0.39) | PDE2A | |
| SCHEMBL22685166 | 0.72 | IDO1 (0.37) | PDE2AIDO1 | |
| SCHEMBL22685191 | 0.70 | WDR91 (0.43) | PDE2AIDO1 | |
| SCHEMBL22686782 | 0.67 | CLK1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |