Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.35 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.35 |
| ▸ | HIPK3 | Q9H422 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | GABBR2 | O75899 | 7/20 | 0.34 |
| ▸ | GABBR1 | Q9UBS5 | 7/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22685253 | 0.74 | PDE2A (0.42) | IDO1 | |
| SCHEMBL22686782 | 0.68 | CLK1 (0.33) | CLK1CLK2HIPK1HIPK2HIPK3 | |
| SCHEMBL26941926 | 0.66 | CLK1 (0.33) | CLK1CLK2HIPK1HIPK2HIPK3 | |
| SCHEMBL24448654 | 0.64 | TRPV4 (0.47) | — | |
| SCHEMBL13838853 | 0.64 | OPRL1 (0.52) | — | |
| SCHEMBL19302652 | 0.64 | SORT1 (0.35) | — | |
| SCHEMBL22685209 | 0.64 | EGLN2 (0.41) | CLK1CLK2HIPK1HIPK2HIPK3 | |
| SCHEMBL22686809 | 0.63 | RAB9A (0.36) | — | |
| SCHEMBL22732516 | 0.63 | USP1 (0.36) | CLK1CLK2HIPK1HIPK2HIPK3 | |
| Ammonia Solution, Strong SCHEMBL793057 | 0.63 | OPRL1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |