Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22685305 | 0.71 | MKNK1 (0.41) | CTSLCTSBCTSSCXCR3ROCK2 | |
| SCHEMBL22685306 | 0.69 | IDO1 (0.41) | CTSLCTSBCTSSCXCR3 | |
| SCHEMBL22685085 | 0.62 | AKT1 (0.38) | CTSLCTSBCTSSCXCR3ROCK2 | |
| SCHEMBL22686792 | 0.61 | PDE2A (0.43) | CXCR3 | |
| SCHEMBL22686795 | 0.60 | BTK (0.38) | CTSLCTSBCTSS | |
| SCHEMBL22685301 | 0.60 | CTSL (0.40) | CTSLCTSBCTSS | |
| SCHEMBL28417132 | 0.59 | CTSL (0.48) | CTSLCTSBCTSS | |
| SCHEMBL22685090 | 0.59 | CD274 (0.43) | CTSLCTSBCTSSROCK2 | |
| SCHEMBL22657417 | 0.58 | MKNK1 (0.45) | CTSLCTSBCTSSCXCR3 | |
| SCHEMBL22657410 | 0.58 | WDR91 (0.40) | CTSLCTSBCTSSCXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |