Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | MDH2 | P40926 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30785022 | 0.83 | HTT (0.39) | ALDH1A1CCNB2CDK1CCNB1GSK3B | |
| SCHEMBL28459022 | 0.80 | LMNA (0.48) | LMNAALDH1A1CCNB2CDK1CCNB1 | |
| SCHEMBL6352617 | 0.79 | ALDH1A1 (0.47) | LMNAALDH1A1CCNB2CDK1CCNB1 | |
| SCHEMBL22938423 | 0.79 | LMNA (0.47) | LMNAALDH1A1CCNB2CDK1CCNB1 | |
| SCHEMBL29167520 | 0.76 | LMNA (0.44) | LMNAALDH1A1CCNB2CDK1CCNB1 | |
| SCHEMBL21200136 | 0.73 | MAPK14 (0.42) | ALDH1A1HSD17B10SMN1; SMN2CA12CA1 | |
| SCHEMBL29866826 | 0.73 | MAPK14 (0.42) | ALDH1A1HSD17B10SMN1; SMN2CA12CA1 | |
| SCHEMBL29734620 | 0.70 | CRBN (0.49) | LMNAALDH1A1CCNB2CDK1CCNB1 | |
| SCHEMBL22491528 | 0.70 | CRBN (0.49) | LMNAALDH1A1CCNB2CDK1CCNB1 | |
| SCHEMBL1359221 | 0.70 | CRBN (0.59) | LMNAALDH1A1CCNB2CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025093059-A1 | 3-(AMINO)METHYLENE INDOLINE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF | 徐诺药业(南京)有限公司 | 2025-05-08 | — | — | WO | disclosed |
| CN-117624179-A | 3- (amino) methylene indoline derivative and preparation method and application thereof | 徐诺药业(南京)有限公司 | 2024-03-01 | — | — | CN | disclosed |
| WO-2020234333-A1 | OTHER HETEROAROMATIC COMPOUNDS HAVING ACTIVITY AGAINST RSV | Janssen Sciences Ireland Unlimited Company (IE) | 2020-11-26 | — | — | WO | disclosed |