Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.46 |
| ▸ | MDH2 | P40926 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28459022 | 0.84 | LMNA (0.48) | LMNAALDH1A1CCNB2CDK1CCNB1 | |
| SCHEMBL6352617 | 0.82 | ALDH1A1 (0.47) | LMNAALDH1A1CCNB2CDK1CCNB1 | |
| SCHEMBL22696301 | 0.79 | LMNA (0.44) | LMNAALDH1A1CCNB2CDK1CCNB1 | |
| SCHEMBL29167520 | 0.79 | LMNA (0.44) | LMNAALDH1A1CCNB2CDK1CCNB1 | |
| SCHEMBL2309393 | 0.77 | CDK1 (0.41) | LMNAALDH1A1CCNB2CDK1CCNB1 | |
| SCHEMBL21905584 | 0.76 | ALDH1A1 (0.60) | LMNAALDH1A1CRBNNOTUMHTT | |
| SCHEMBL28998391 | 0.76 | ALDH1A1 (0.44) | LMNAALDH1A1CCNB2CDK1CCNB1 | |
| SCHEMBL31417618 | 0.75 | NOTUM (0.40) | LMNAALDH1A1NOTUMHSD17B10CA12 | |
| SCHEMBL18387621 | 0.75 | NOTUM (0.40) | LMNAALDH1A1NOTUMHSD17B10CA12 | |
| SCHEMBL18739134 | 0.74 | ALDH1A1 (0.42) | LMNAALDH1A1CRBNNOTUMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025067457-A1 | HETEROCYCLIC FUSED RING COMPOUND, AND COMPOSITION AND USE THEREOF | 深圳市塔吉瑞生物医药有限公司 | 2025-04-03 | — | — | WO | disclosed |
| CN-112300129-B | Heterocyclic compounds as BCR-ABL inhibitors | 苏州亚盛药业有限公司 | 2021-09-14 | — | — | CN | disclosed |
| WO-2021018194-A1 | HETEROCYCLIC COMPOUNDS AS BCR-ABL INHIBITORS | ASCENTAGE PHARMA (SUZHOU) CO., LTD. (CN) | 2021-02-04 | — | — | WO | disclosed |
| CN-112300129-A | Heterocyclic compounds as BCR-ABL inhibitors | 苏州亚盛药业有限公司 | 2021-02-02 | — | — | CN | disclosed |