Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.44 |
| ▸ | CDK1 | P06493 | 2/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.44 |
| ▸ | MDH2 | P40926 | 2/20 | 0.44 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6352617 | 0.87 | ALDH1A1 (0.47) | LMNAALDH1A1CCNB2CDK1CCNB1 | |
| SCHEMBL28459022 | 0.80 | LMNA (0.48) | LMNAALDH1A1CCNB2CDK1CCNB1 | |
| SCHEMBL22938423 | 0.79 | LMNA (0.47) | LMNAALDH1A1CCNB2CDK1CCNB1 | |
| SCHEMBL22696301 | 0.76 | LMNA (0.44) | LMNAALDH1A1CCNB2CDK1CCNB1 | |
| SCHEMBL12431680 | 0.73 | CCNB2 (0.41) | LMNAALDH1A1CCNB2CDK1CCNB1 | |
| SCHEMBL2309393 | 0.73 | CDK1 (0.41) | LMNAALDH1A1CCNB2CDK1CCNB1 | |
| SCHEMBL12807357 | 0.71 | KDM4E (0.57) | LMNAALDH1A1HTTALOX15HSD17B10 | |
| SCHEMBL22491528 | 0.70 | CRBN (0.49) | LMNAALDH1A1CCNB2CDK1CCNB1 | |
| SCHEMBL29734620 | 0.70 | CRBN (0.49) | LMNAALDH1A1CCNB2CDK1CCNB1 | |
| SCHEMBL1359221 | 0.70 | CRBN (0.59) | LMNAALDH1A1CCNB2CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117624014-A | 3- (indolylamino) methylene indoline derivative and preparation method and application thereof | 徐诺药业(南京)有限公司 | 2024-03-01 | — | — | CN | disclosed |