Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL568870 | 0.85 | ALDH1A1 (0.41) | ALDH1A1KMT2ANAPRTKDM4ECYP1A2 | |
| SCHEMBL8131766 | 0.83 | ALDH1A1 (0.41) | ALDH1A1KMT2ANAPRTKDM4ECYP1A2 | |
| SCHEMBL13712395 | 0.82 | F7 (0.39) | ALDH1A1KMT2ANAPRTKDM4ECYP1A2 | |
| SCHEMBL117564 | 0.80 | F7 (0.38) | ALDH1A1NAPRTKDM4ECYP1A2CYP3A4 | |
| SCHEMBL28011360 | 0.80 | NAPRT (0.38) | ALDH1A1KMT2ANAPRTKDM4ECYP1A2 | |
| SCHEMBL8515494 | 0.80 | NAPRT (0.38) | ALDH1A1KMT2ANAPRTKDM4ECYP1A2 | |
| Pyridine SCHEMBL29132336 | 0.80 | ENPP2 (0.39) | ALDH1A1KMT2ANAPRTCYP19A1 | |
| SCHEMBL1977767 | 0.80 | CYP2A6 (0.40) | ALDH1A1KMT2ANAPRTKDM4ECYP1A2 | |
| SCHEMBL3515822 | 0.79 | CHRNB2 (0.38) | ALDH1A1KMT2ANAPRTKDM4ECYP3A4 | |
| SCHEMBL3515821 | 0.79 | ALDH1A1 (0.41) | ALDH1A1KMT2ANAPRTKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192989-A2 | PHTHALAZINONE COMPOUNDS AS PARP7 INHIBITORS | AZKARRA THERAPEUTICS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |
| WO-2015065336-A1 | RESPIRATORY SYNCYTIAL VIRUS INHIBITORS | MEDIVIR AB (SE) | 2015-05-07 | — | — | WO | disclosed |
| WO-2011088160-A2 | NOVEL CYP17 INHIBITORS | BIOMARIN PHARMACEUTICAL INC. (US) | 2011-07-21 | — | — | WO | disclosed |
| US-20050118209-A1 | Cosmetic or dermatological preparations for preventing damages to skin caused by peroxides | BASF AKTIENGESELLSCHAFT (DE) | 2005-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050118209-A1 | Cosmetic or dermatological preparations for preventing damages to skin caused by peroxides | CAT, LPO, GPX4 | ALDH1A1 184/4885KMT2A 2682/4885NAPRT 1056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.