Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.43 |
| ▸ | NOS1 | P29475 | 2/20 | 0.43 |
| ▸ | NOS2 | P35228 | 2/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.30 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22703139 | 0.88 | NOS3 (0.41) | NOS3NOS1NOS2ABCG2ABCB1 | |
| SCHEMBL17747031 | 0.84 | LTA4H (0.33) | — | |
| SCHEMBL17747029 | 0.84 | LTA4H (0.33) | — | |
| SCHEMBL30932937 | 0.74 | L3MBTL1 (0.43) | NOS3NOS1NOS2ABCG2 | |
| SCHEMBL24648741 | 0.73 | TSHR (0.42) | NOS3NOS1NOS2 | |
| SCHEMBL23566825 | 0.73 | NOS2 (0.55) | NOS3NOS1NOS2ABCG2 | |
| SCHEMBL23566826 | 0.73 | NOS2 (0.55) | NOS3NOS1NOS2ABCG2 | |
| SCHEMBL13625040 | 0.73 | MGMT (0.31) | — | |
| SCHEMBL18906771 | 0.72 | TTR (0.34) | ABCG2ABCB1 | |
| SCHEMBL18906417 | 0.72 | TTR (0.34) | ABCG2ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200369613-A1 | INTEGRIN LIGANDS AND USES THEREOF | SIXTH STREETLENDING PARTNERS, AS THE ADMINISTRATIVE AGENT | 2020-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200369613-A1 | INTEGRIN LIGANDS AND USES THEREOF | ITGB6, ITGA6, ITGAV | NOS3 4814/4885NOS1 4695/4885NOS2 4802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.