SCHEMBL2270565

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2271137	0.94	HDAC2 (0.74)	MEN1KMT2APOLBHDAC2PYGM
	SCHEMBL2275393	0.89	HDAC2 (0.73)	MEN1KMT2AHDAC2ACLYRAB9A
	SCHEMBL2270661	0.88	ACLY (0.58)	MEN1KMT2APOLBHDAC2ACLY
	SCHEMBL2269165	0.88	MEN1 (0.69)	MEN1KMT2AHDAC2ACLYRAB9A
	SCHEMBL2275720	0.87	SUCNR1 (0.73)	MEN1KMT2AHDAC2ACLYRAB9A
	SCHEMBL14075227	0.86	MEN1 (0.78)	MEN1KMT2APYGMRAB9ASMN1; SMN2
	SCHEMBL12369428	0.85	HDAC2 (0.72)	MEN1KMT2APOLBHDAC2RAB9A
	SCHEMBL2271177	0.85	PYGM (0.72)	MEN1KMT2APYGMRAB9ASMN1; SMN2
	SCHEMBL1315613	0.85	HDAC2 (0.56)	MEN1KMT2APOLBHDAC2PYGM
	SCHEMBL2275453	0.84	ACLY (0.76)	MEN1KMT2AHDAC2ACLYRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.