SCHEMBL227146

SCHEMBL227146

CCCCCCCCCCCCC(C)(CC(S)(c1cc(C(C)(C)C)c(O)cc1C)c1cc(C(C)(C)C)c(O)cc1C)c1cc(C(C)(C)C)c(O)cc1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 3/20 0.41
TP53 P04637 2/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
ALDH1A1 P00352 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
CYP3A4 P08684 1/20 0.37
TSHR P16473 1/20 0.37
MAPK1 P28482 1/20 0.37
HIF1A Q16665 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CNR1 P21554 10/20 0.36
CNR2 P34972 9/20 0.36
KDM4E B2RXH2 1/20 0.35
CYP1A2 P05177 1/20 0.35
MAPT P10636 1/20 0.35
ATP2A2 P16615 1/20 0.35
ATP2A3 Q93084 1/20 0.35
ESR1 P03372 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29279397 0.80 ALOX15 (0.43) ALOX15TP53CYP2D6CYP2C9CYP2C19
SCHEMBL29400338 0.77 ALOX15 (0.43) ALOX15TP53CYP2D6CYP2C9CYP2C19
SCHEMBL39144 0.77 ALOX15 (0.43) ALOX15TP53CYP2D6CYP2C9CYP2C19
SCHEMBL5086030 0.77 ALOX15 (0.49) ALOX15TP53CYP2D6CYP2C9CYP2C19
SCHEMBL29421162 0.76 ALOX15 (0.46) ALOX15TP53CYP2D6CYP2C9CYP2C19
SCHEMBL78065 0.76 ALOX15 (0.46) ALOX15TP53CYP2D6CYP2C9CYP2C19
SCHEMBL464938 0.75 ALOX15 (0.42) ALOX15TP53CYP2D6CYP2C9CYP2C19
SCHEMBL9351488 0.75 ALOX15 (0.45) ALOX15TP53CYP2D6CYP2C9CYP2C19
SCHEMBL7748636 0.74 ALOX15 (0.46) ALOX15TP53CYP2D6CYP2C9CYP2C19
SCHEMBL97186 0.74 ALOX15 (0.46) ALOX15TP53CYP2D6CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260103652-A1 MACROMOLECULAR CORROSION (McIn) INHIBITORS: STRUCTURES, METHODS OF MAKING AND USING THE SAME POLNOX CORP (US) 2026-04-16 US disclosed
US-12492352-B2 Macromolecular corrosion (MCIN) inhibitors: structures, methods of making and using the same POLNOX CORPORATION (US) 2025-12-09 US disclosed
US-20230159841-A1 MACROMOLECULAR CORROSION (MCIN) INHIBITORS: STRUCTURES, METHODS OF MAKING AND USING THE SAME POLNOX CORPORATION 2023-05-25 US disclosed
US-11578285-B2 Macromolecular corrosion (McIn) inhibitors: structures, methods of making and using the same POLNOX CORPORATION (US) 2023-02-14 US disclosed
EP-3071544-B1 MACROMOLECULAR ANTIOXIDANTS BASED ON DUAL TYPE MOIETY PER MOLECULE: STRUCTURES METHODS OF MAKING AND USING THE SAME POLNOX CORP (US) 2022-07-06 EP disclosed
US-11060027-B2 Macromolecular antioxidants based on dual type moiety per molecule: structures, methods of making and using the same POLNOX CORPORATION (US) 2021-07-13 US disclosed
US-20210130722-A1 MACROMOLECULAR CORROSION (MCIN) INHIBITORS: STRUCTURES, METHODS OF MAKING AND USING THE SAME POLNOX CORPORATION 2021-05-06 US disclosed
US-20200392406-A1 MACROMOLECULAR ANTIOXIDANTS BASED ON DUAL TYPE MOIETY PER MOLECULE: STRUCTURES, METHODS OF MAKING AND USING THE SAME POLNOX CORPORATION 2020-12-17 US disclosed
US-10683455-B2 Macromolecular antioxidants based on dual type moiety per molecule: structures, methods of making and using the same POLNOX CORPORATION (US) 2020-06-16 US disclosed
US-20190292454-A1 Macromolecular Antioxidants Based On Dual Type Moiety Per Molecule: Structures, Methods Of Making And Using The Same POLNOX CORPORATION 2019-09-26 US disclosed
US-5073278-A Oxidation resistant CIBA-GEIGY CORPORATION (US) 1991-12-17 US disclosed
US-5002698-A Anti-Wear Agents, Extreme Pressure Additives CIBA-GEIGY CORPORATION (US) 1991-03-26 US disclosed
US-4963276-A MIXTURE OF AROMATIC AMINE AND ORGANOSULFUR COMPOUND CIBA-GEIGY CORPORATION (US) 1990-10-16 US disclosed
EP-0391649-A2 Improved ashless lubricant compositions for internal combustion engines EXXON CHEMICAL PATENTS INC. (US) 1990-10-10 EP disclosed
EP-0391651-A2 Improved low ash lubricant composition for internal combustion engines EXXON CHEMICAL PATENTS INC. (US) 1990-10-10 EP disclosed
US-4925580-A HYDRALIC OILS; CORROSION AND WEAR RESISTANCE CIBA-GEIGY CORPORATION (US) 1990-05-15 US disclosed
US-4917809-A OIL-SOLUBLE 5-MEMBERED RING HETEROCYCLIC COMPOUND, WHICH MAY BE BENZO-FUSED, AND PHOSPHORUS COMPOUND CIBA-GEIGY CORPORATION (US) 1990-04-17 US disclosed
US-4863621-A WEAR RESISTANCE, EXTREME PRESSURE LUBRICANTS CIBA-GEIGY CORPORATION (US) 1989-09-05 US disclosed
US-4737300-A LUBRICANTS, STABILIZERS CIBA-GEIGY CORPORATION (US) 1988-04-12 US disclosed
EP-0220136-A2 Boric-acid complexes CIBA-GEIGY AG (CH) 1987-04-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11060027-B2 Macromolecular antioxidants based on dual type moiety per molecule: structures, methods of making and using the same LPO, GPX4, DUOX2 ALOX15 479/4885TP53 2027/4885CYP2D6 627/4885
US-11578285-B2 Macromolecular corrosion (McIn) inhibitors: structures, methods of making and using the same MB, NCLN, CPN1 ALOX15 1763/4885TP53 2097/4885CYP2D6 4120/4885
US-10683455-B2 Macromolecular antioxidants based on dual type moiety per molecule: structures, methods of making and using the same LPO, GPX4, DUOX2 ALOX15 479/4885TP53 2027/4885CYP2D6 627/4885
US-20210130722-A1 MACROMOLECULAR CORROSION (MCIN) INHIBITORS: STRUCTURES, METHODS OF MAKING AND USING THE SAME MB, NCLN, CPN1 ALOX15 1763/4885TP53 2097/4885CYP2D6 4120/4885
US-20190292454-A1 Macromolecular Antioxidants Based On Dual Type Moiety Per Molecule: Structures, Methods Of Making And Using The Same LPO, GPX4, DUOX2 ALOX15 479/4885TP53 2027/4885CYP2D6 627/4885
US-20200392406-A1 MACROMOLECULAR ANTIOXIDANTS BASED ON DUAL TYPE MOIETY PER MOLECULE: STRUCTURES, METHODS OF MAKING AND USING THE SAME LPO, GPX4, DUOX2 ALOX15 479/4885TP53 2027/4885CYP2D6 627/4885
US-12492352-B2 Macromolecular corrosion (MCIN) inhibitors: structures, methods of making and using the same MB, NCLN, CPN1 ALOX15 1763/4885TP53 2097/4885CYP2D6 4120/4885
US-20260103652-A1 MACROMOLECULAR CORROSION (McIn) INHIBITORS: STRUCTURES, METHODS OF MAKING AND USING THE SAME MPO, CYC1, CBR1 ALOX15 1702/4885TP53 2544/4885CYP2D6 2312/4885
US-20230159841-A1 MACROMOLECULAR CORROSION (MCIN) INHIBITORS: STRUCTURES, METHODS OF MAKING AND USING THE SAME MB, NCLN, CPN1 ALOX15 1763/4885TP53 2097/4885CYP2D6 4120/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.