SCHEMBL2270621

SCHEMBL2270621

O=C(Nc1cc(Oc2ccccc2)ccc1C(=O)O)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GALK1 P51570 1/20 0.68
CASP6 P55212 1/20 0.68
MCL1 Q07820 1/20 0.68
PLEC Q15149 1/20 0.68
TDP1 Q9NUW8 1/20 0.68
DHODH Q02127 1/20 0.63
SERPINE1 P05121 2/20 0.62
IGF2BP2 Q9Y6M1 1/20 0.58
ACLY P53396 1/20 0.57
HPSE Q9Y251 1/20 0.57
NR1H4 Q96RI1 1/20 0.55
PYGL P06737 1/20 0.54
PYGM P11217 1/20 0.54
NPC1 O15118 1/20 0.53
RAB9A P51151 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2271588 0.92 SERPINE1 (0.64) GALK1CASP6MCL1PLECTDP1
SCHEMBL2272033 0.91 ACLY (0.62) GALK1CASP6MCL1PLECTDP1
SCHEMBL2275544 0.90 FABP1 (0.61) GALK1CASP6MCL1PLECTDP1
SCHEMBL2276745 0.90 SERPINE1 (0.65) GALK1CASP6MCL1PLECTDP1
SCHEMBL2273634 0.88 SERPINE1 (0.60) GALK1CASP6MCL1PLECTDP1
SCHEMBL2272043 0.88 SERPINE1 (0.75) GALK1CASP6MCL1PLECTDP1
SCHEMBL2271007 0.88 MEN1 (0.69) SERPINE1HPSENR1H4PYGM
SCHEMBL2276169 0.88 SERPINE1 (0.60) GALK1CASP6MCL1PLECTDP1
SCHEMBL2275467 0.88 CYP2C9 (0.63) GALK1CASP6MCL1PLECTDP1
SCHEMBL2272774 0.86 KMT2A (0.63) GALK1CASP6MCL1PLECTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7999132-B2 Anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO., LTD. (JP) 2011-08-16 US disclosed
US-20090240052-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2009-09-24 US disclosed
EP-1820795-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2007-08-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090240052-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF MMP13, MMP26, MMP11 GALK1 709/4885CASP6 84/4885MCL1 1774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.