SCHEMBL2272006

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2272853	0.96	ACLY (0.60)	ACLYSERPINE1DHODHHDAC1HDAC2
	SCHEMBL14428491	0.90	SERPINE1 (0.53)	ACLYSERPINE1DHODHHDAC1HDAC2
	SCHEMBL2270222	0.88	DHODH (0.77)	ACLYSERPINE1DHODHHDAC1HDAC2
	SCHEMBL2269037	0.88	ACLY (0.59)	ACLYSERPINE1DHODHHDAC1HDAC2
	SCHEMBL2273168	0.85	SERPINE1 (0.61)	ACLYSERPINE1DHODHMEN1MAPT
	SCHEMBL2275453	0.85	ACLY (0.76)	ACLYSERPINE1DHODHHDAC1HDAC2
	SCHEMBL2274895	0.85	ACLY (0.56)	ACLYSERPINE1DHODHHDAC1HDAC2
	SCHEMBL2275413	0.84	HDAC1 (0.50)	ACLYSERPINE1DHODHHDAC1HDAC2
	SCHEMBL2272605	0.83	DHODH (0.73)	ACLYSERPINE1DHODHHDAC1HDAC2
	SCHEMBL27696974	0.83	SERPINE1 (0.46)	ACLYSERPINE1DHODHHDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.