SCHEMBL2273168

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2272853	0.89	ACLY (0.60)	SERPINE1PKMKMT2AMEN1GRIK1
	SCHEMBL14429559	0.89	SERPINE1 (0.52)	SERPINE1PKMKMT2AMEN1GRIK1
	SCHEMBL2272006	0.85	ACLY (0.62)	SERPINE1PKMKMT2AMEN1GRIK1
	SCHEMBL2269037	0.83	ACLY (0.59)	SERPINE1PKMKMT2AMEN1GRIK1
	SCHEMBL2275558	0.82	SERPINE1 (0.58)	SERPINE1PKMKMT2AMEN1GRIK1
	SCHEMBL2273439	0.82	SERPINE1 (0.46)	SERPINE1PKMKMT2AMEN1GRIK1
	SCHEMBL27696869	0.81	ALDH1A1 (0.47)	SERPINE1PKMKMT2AMEN1GRIK1
	SCHEMBL2271446	0.81	PYGM (0.50)	SERPINE1PKMKMT2AMEN1AOC2
	SCHEMBL2274028	0.79	PKM (0.52)	SERPINE1PKMKMT2AMEN1GRIK1
	SCHEMBL2271365	0.77	PKM (0.70)	SERPINE1PKMKMT2AMEN1GRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.