SCHEMBL2274895

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2268120	0.94	ACLY (0.48)	ACLYALDH1A1HDAC1DHODHHDAC2
	SCHEMBL2269570	0.91	ACLY (0.54)	ACLYALDH1A1SUCNR1SERPINE1GRIK1
	SCHEMBL2270475	0.87	HDAC1 (0.43)	ACLYALDH1A1HDAC1HDAC2HDAC3
	SCHEMBL12395652	0.86	ACLY (0.41)	ACLYALDH1A1HDAC1DHODHHDAC2
	SCHEMBL2269037	0.85	ACLY (0.59)	ACLYHDAC1DHODHHDAC2HDAC3
	SCHEMBL2272006	0.85	ACLY (0.62)	ACLYHDAC1DHODHHDAC2HDAC3
	SCHEMBL1315751	0.85	ACLY (0.64)	ACLYALDH1A1HDAC1DHODHHDAC2
	SCHEMBL12369599	0.84	HDAC2 (0.52)	ACLYALDH1A1HDAC2SERPINE1MEN1
	SCHEMBL2276851	0.84	CHRNB4 (0.45)	ACLYALDH1A1HDAC1HDAC2SERPINE1
	SCHEMBL2270812	0.84	ALDH1A1 (0.47)	ALDH1A1SERPINE1KDM4DKDM4CMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.