SCHEMBL7363535

SCHEMBL7363535

OCC[SiH2]c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.40
TSHR P16473 1/20 0.38
ALDH1A1 P00352 2/20 0.36
RECQL P46063 1/20 0.36
GAA P10253 1/20 0.33
POLB P06746 1/20 0.31
MAPK1 P28482 1/20 0.31
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
GLA P06280 1/20 0.30
CA3 P07451 1/20 0.30
CA4 P22748 1/20 0.30
CA9 Q16790 1/20 0.30
CA14 Q9ULX7 1/20 0.30
FFAR1 O14842 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9510289 0.78
SCHEMBL29926801 0.76 ALDH1A1 (0.32) TDP1ALDH1A1GAAMAPK1
SCHEMBL3682860 0.74 TP53 (0.38) ALDH1A1GAAMAPK1FFAR1
SCHEMBL28598231 0.74 LOXL2 (0.32) ALDH1A1MAPK1
SCHEMBL2272019 0.74 ALDH1A1 (0.31) TSHRALDH1A1MAPK1
Ethylene Glycol SCHEMBL21616542 0.72 TDP1 (0.43) TDP1TSHRALDH1A1RECQLGAA
SCHEMBL13169411 0.72 MAOB (0.41) TDP1ALDH1A1CA1CA2FFAR1
SCHEMBL3684087 0.72 ALDH1A1 (0.46) TDP1TSHRALDH1A1CA1CA2
SCHEMBL28209224 0.72 MAOA (0.44)
SCHEMBL1274186 0.70 LTA4H (0.38) TDP1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120059264-A Universal functional coating material and preparation method thereof 陕西师范大学 2025-05-30 CN claimed
CN-120059264-A Universal functional coating material and preparation method thereof 陕西师范大学 2025-05-30 CN disclosed
US-20130204027-A1 PRODUCTION OF SILAOXACYCLES WACKER CHEMIE AG (DE) 2013-08-08 US disclosed
EP-2192116-A1 INDAZOLE ACRYLIC ACID AMIDE COMPOUND Mitsubishi Tanabe Pharma Corporation (JP) 2010-06-02 EP disclosed
EP-0846127-A1 ACYLATED OLIGOPEPTIDE DERIVATIVES HAVING CELL SIGNAL INHIBITING ACTIVITY Novartis AG (CH) 1998-06-10 EP disclosed
WO-1997008193-A1 ACYLATED OLIGOPEPTIDE DERIVATIVES HAVING CELL SIGNAL INHIBITING ACTIVITY NOVARTIS AG (CH) 1997-03-06 WO disclosed
WO-1997007131-A1 ACYLATED OLIGOPEPTIDES CONTAINING PHOSPHOTYROSINE AS INHIBITORS OF PROTEIN TYROSINE KINASES NOVARTIS AG (CH) 1997-02-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130204027-A1 PRODUCTION OF SILAOXACYCLES OSTC, POLR2E, HAO2 TDP1 3930/4885TSHR 3020/4885ALDH1A1 1736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.