Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13169411 | 0.95 | MAOB (0.41) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL13169407 | 0.89 | MAOA (0.42) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL15835141 | 0.86 | SIGMAR1 (0.46) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL13169394 | 0.79 | ALDH1A1 (0.38) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL2272019 | 0.77 | ALDH1A1 (0.31) | ALDH1A1TSHR | |
| SCHEMBL13169395 | 0.76 | PTGS2 (0.36) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL8382309 | 0.76 | ALDH1A1 (0.52) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| Hydrochloric Acid SCHEMBL1030795 | 0.74 | ALDH1A1 (0.50) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL3683423 | 0.74 | TSHR (0.46) | ALDH1A1HPGDALOX15ALOX12CASP1 | |
| SCHEMBL29926801 | 0.74 | ALDH1A1 (0.32) | ALDH1A1HPGDALOX12HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516871-A | Diphenylsiloxane oligomers functionalized at both terminals and methods for the preparation thereof | DOW CORNING ASIA, LTD. (JP) | 1996-05-14 | — | — | US | claimed |
| US-5502229-A | ENDCAPPING | DOW CORNING ASIA, LTD. (JP) | 1996-03-26 | — | — | US | claimed |
| CN-114874244-B | Preparation method of aryl borate or alkyl borate compound | 中国科学院兰州化学物理研究所 | 2023-12-01 | — | — | CN | disclosed |
| WO-2023277824-A2 | DIVERSE FUNCTIONALIZATION OF HYDROSILANES AND PROGRAMMABLE SYNTHESIS OF MULTISUBSTITUTED ORGANOSILANES ENABLED BY NEUTRAL EOSIN Y PHOTOCATALYSIS | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2023-01-05 | — | — | WO | disclosed |
| CN-114874244-A | Preparation method of arylboronic acid ester or alkyl boronate compound | 中国科学院兰州化学物理研究所 | 2022-08-09 | — | — | CN | disclosed |
| US-11273432-B2 | Beta-diketiminate manganese catalysts for hydrosilylation, hydroboration, and dehydrogenative pnictogen-silicon and pnictogen-boron bond formation | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2022-03-15 | — | — | US | disclosed |
| CN-106573235-B | Iron hydrosilylate catalyst | 国立大学法人九州大学 | 2020-07-07 | — | — | CN | disclosed |
| EP-2994474-B1 | SATURATED AND UNSATURATED SILAHYDROCARBONS VIA IRON AND COBALT PYRIDINE DIIMINE CATALYZED OLEFIN SILYLATION | MOMENTIVE PERFORMANCE MAT INC (US) | 2017-12-20 | — | — | EP | disclosed |
| CN-106573235-A | Hydrosilylation iron catalyst | 国立大学法人九州大学 | 2017-04-19 | — | — | CN | disclosed |
| US-9371339-B2 | Saturated and unsaturated silahydrocarbons via iron and cobalt pyridine diimine catalyzed olefin silylation | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2016-06-21 | — | — | US | disclosed |
| EP-2994474-A1 | SATURATED AND UNSATURATED SILAHYDROCARBONS VIA IRON AND COBALT PYRIDINE DIIMINE CATALYZED OLEFIN SILYLATION | Momentive Performance Materials Inc. (US) | 2016-03-16 | — | — | EP | disclosed |
| US-20080031830-A1 | Dental Composition Containing an Epoxy Functional Carbosilane Compound | 3M DEUTSCHLAND GMBH (DE) | 2008-02-07 | — | — | US | disclosed |
| CN-101060827-A | Dental compositions comprising epoxy-functional carbosilane compounds | 3M ESPE AG (DE) | 2007-10-24 | — | — | CN | disclosed |
| EP-1765265-A1 | DENTAL COMPOSITION CONTAINING AN EPOXY FUNCTIONAL CARBOSILANE COMPOUND | 3M Espe AG (DE) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006005369-A1 | DENTAL COMPOSITION CONTAINING AN EPOXY FUNCTIONAL CARBOSILANE COMPOUND | 3M ESPE AG (DE) | 2006-01-19 | — | — | WO | disclosed |
| CN-1618877-A | Polycarbonate resin composition for producing substrate for optical information medium | ASAHI CHEMICAL CORP (JP) | 2005-05-25 | — | — | CN | disclosed |
| CN-1090642-C | Polycarbonate comprising different kinds of bonding units and process for preparation thereof | ASAHI CHEMICAL IND (JP) | 2002-09-11 | — | — | CN | disclosed |
| CN-1206425-A | Polycarbonate comprising different kinds of bonding units and process for preparation thereof | ASAHI CHEMICAL IND (JP) | 1999-01-27 | — | — | CN | disclosed |
| US-5516871-A | Diphenylsiloxane oligomers functionalized at both terminals and methods for the preparation thereof | DOW CORNING ASIA, LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5502229-A | ENDCAPPING | DOW CORNING ASIA, LTD. (JP) | 1996-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11273432-B2 | Beta-diketiminate manganese catalysts for hydrosilylation, hydroboration, and dehydrogenative pnictogen-silicon and pnictogen-boron bond formation | SLC6A12, PNN, PNKP | ALDH1A1 1744/4885HPGD 40/4885ALOX15 1220/4885 |
| US-20080031830-A1 | Dental Composition Containing an Epoxy Functional Carbosilane Compound | EPX, TAS2R41, TAS1R1 | ALDH1A1 1405/4885HPGD 1201/4885ALOX15 216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.