Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.49 |
| ▸ | CDK9 | P50750 | 1/20 | 0.49 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | ERN1 | O75460 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22721440 | 1.00 | ALDH1A1 (0.50) | ALDH1A1KDM4ETSHRTDP1CCNT1 | |
| SCHEMBL1271246 | 0.82 | MAOA (0.59) | ALDH1A1KDM4EMAOACYP3A4HPGD | |
| Hydrochloric Acid SCHEMBL9623496 | 0.81 | MAOA (0.61) | ALDH1A1KDM4EMAOACYP3A4HPGD | |
| SCHEMBL4059355 | 0.79 | ALDH1A1 (0.61) | ALDH1A1KDM4ETSHRTDP1ERN1 | |
| SCHEMBL1487621 | 0.78 | ALDH1A1 (0.71) | ALDH1A1KDM4ETSHRTDP1ERN1 | |
| SCHEMBL28125417 | 0.77 | MAOA (0.44) | KDM4ETSHRMAOACYP3A4 | |
| SCHEMBL11299778 | 0.76 | ALDH1A1 (0.57) | ALDH1A1KDM4ETSHRTDP1ERN1 | |
| SCHEMBL24165355 | 0.76 | MAOA (0.53) | ALDH1A1MAOACYP3A4 | |
| SCHEMBL3894423 | 0.76 | MAOA (0.53) | ALDH1A1MAOACYP3A4 | |
| SCHEMBL1605930 | 0.75 | ERN1 (0.49) | ALDH1A1KDM4ETSHRTDP1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12559504-B2 | Benzotriazole derivative | UBE CORPORATION (JP) | 2026-02-24 | — | — | US | disclosed |
| EP-3978073-B1 | 1H-BENZO[D][1,2,3]TRIAZOLE DERIVATIVES AS KEAP1 INHIBITORS FOR THE TREATMENT OF RENAL DISEASES | UBE CORP (JP) | 2025-10-15 | — | — | EP | disclosed |
| CN-114174289-B | Benzotriazole derivatives | ＵＢＥ株式会社 | 2025-03-07 | — | — | CN | disclosed |
| US-20220259223-A1 | BENZOTRIAZOLE DERIVATIVE | UBE INDUSTRIES, LTD. (JP) | 2022-08-18 | — | — | US | disclosed |
| EP-3978073-A1 | BENZOTRIAZOLE DERIVATIVE | Ube Industries, Ltd. (JP) | 2022-04-06 | — | — | EP | disclosed |
| CN-114174289-A | Benzotriazole derivatives | 宇部兴产株式会社 | 2022-03-11 | — | — | CN | disclosed |
| WO-2020241853-A1 | BENZOTRIAZOLE DERIVATIVE | 宇部興産株式会社 | 2020-12-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12559504-B2 | Benzotriazole derivative | KEAP1, NFE2L2, NCOR1 | ALDH1A1 198/4885KDM4E 502/4885TSHR 2245/4885 |
| US-20220259223-A1 | BENZOTRIAZOLE DERIVATIVE | KEAP1, NFE2L2, BACH1 | ALDH1A1 301/4885KDM4E 729/4885TSHR 4053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.