Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM2 | O94759 | 3/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2272147 | 1.00 | TRPM2 (0.77) | TRPM2ALDH1A1HTTMAPTTDP1 | |
| SCHEMBL2273176 | 0.89 | TRPM2 (0.77) | TRPM2ALDH1A1HTTMAPTTDP1 | |
| SCHEMBL2273179 | 0.89 | TRPM2 (0.77) | TRPM2ALDH1A1HTTMAPTTDP1 | |
| SCHEMBL6791025 | 0.88 | ALDH1A1 (0.80) | TRPM2ALDH1A1HTTMAPTTDP1 | |
| SCHEMBL6791019 | 0.88 | ALDH1A1 (0.80) | TRPM2ALDH1A1HTTMAPTTDP1 | |
| SCHEMBL8065895 | 0.86 | TRPV1 (0.67) | TRPM2ALDH1A1HTTMAPTTDP1 | |
| SCHEMBL8065896 | 0.86 | TRPV1 (0.67) | TRPM2ALDH1A1HTTMAPTTDP1 | |
| SCHEMBL2269338 | 0.85 | TRPM2 (0.75) | TRPM2MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL2269335 | 0.85 | TRPM2 (0.75) | TRPM2MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL2276495 | 0.85 | ALDH1A1 (0.61) | TRPM2ALDH1A1HTTMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101094829-B | novel anthranilic acid derivative or salt thereof | TOYAMA CHEMICAL CO.,LTD. (JP) | 2012-02-08 | — | — | CN | disclosed |
| US-7999132-B2 | Anthranilic acid derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2011-08-16 | — | — | US | disclosed |
| US-20090240052-A1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2009-09-24 | — | — | US | disclosed |
| CN-101094829-A | Novel anthranilic acid derivative or salt thereof | TOYAMA CHEMICAL CO LTD (JP) | 2007-12-26 | — | — | CN | disclosed |
| EP-1820795-A1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2007-08-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090240052-A1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | MMP13, MMP26, MMP11 | TRPM2 3539/4885ALDH1A1 645/4885HTT 3716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.