Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30538846 | 0.91 | ACE (0.49) | OPRK1MMP1MMP3MMP9CTSC | |
| SCHEMBL30538864 | 0.91 | ACE (0.49) | OPRK1MMP1MMP3MMP9CTSC | |
| SCHEMBL22604579 | 0.89 | OPRK1 (0.55) | OPRK1ALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL21339517 | 0.89 | OPRK1 (0.55) | OPRK1ALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL22349744 | 0.89 | OPRK1 (0.55) | OPRK1ALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL17446713 | 0.86 | OPRK1 (0.55) | OPRK1ALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL30565197 | 0.84 | LTA4H (0.48) | ALDH1A1CTSSCTSK | |
| SCHEMBL29755521 | 0.84 | ACE (0.55) | MMP1MMP3HDAC3HDAC4HDAC1 | |
| SCHEMBL30291613 | 0.83 | MMP1 (0.53) | OPRK1MMP1MMP3MMP9HDAC3 | |
| SCHEMBL17254256 | 0.82 | TDP1 (0.56) | OPRK1KLK5MMP1MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10851134-B2 | Method for preparing cyclopeptide | NATIONAL TSING HUA UNIVERSITY (TW) | 2020-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10851134-B2 | Method for preparing cyclopeptide | PPIB, PPIA, PPIL1 | OPRK1 4213/4885ALDH1A1 2398/4885THRB 3971/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.