SCHEMBL2272453

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1320352	0.93	ACMSD (0.68)	ACLYKCNMA1HDAC1DHODHACMSD
	SCHEMBL1318525	0.91	ACLY (0.67)	ACLYKCNMA1HDAC1DHODHACMSD
	SCHEMBL27696863	0.90	ACLY (0.62)	ACLYKCNMA1HDAC1SUCNR1
	SCHEMBL13206537	0.87	ACLY (0.59)	ACLYKCNMA1HDAC1DHODHACMSD
	SCHEMBL13206516	0.87	ACLY (0.61)	ACLYHDAC1DHODHACMSDHNF4A
	SCHEMBL1316633	0.86	ACLY (0.57)	ACLYHDAC1DHODHACMSDLMNA
	SCHEMBL1317521	0.86	ACLY (0.68)	ACLYKCNMA1ACMSDHNF4ASUCNR1
	SCHEMBL2272508	0.85	ACLY (0.63)	ACLYHDAC1DHODHHTTSUCNR1
	SCHEMBL1315890	0.85	ACLY (0.67)	ACLYKCNMA1HDAC1ACMSDHNF4A
	SCHEMBL13206145	0.85	ACLY (0.56)	ACLYKCNMA1HDAC1DHODHACMSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.