Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 3/20 | 0.42 |
| ▸ | ATP4B | P51164 | 3/20 | 0.42 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.36 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.36 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22729864 | 0.82 | LMNA (0.41) | ATP4AATP4BHCAR1GAAALDH1A1 | |
| SCHEMBL22729533 | 0.81 | MAPT (0.42) | ATP4AATP4BHCAR1GAASIGMAR1 | |
| SCHEMBL22729792 | 0.75 | HCAR1 (0.41) | ATP4AATP4BHCAR1GAAALDH1A1 | |
| SCHEMBL22729543 | 0.74 | BRD4 (0.44) | GAAALDH1A1KDM4EPOLBKMT2A | |
| SCHEMBL22729549 | 0.72 | SCN9A (0.41) | GAAALDH1A1HPGDCTDSP1KDM4E | |
| SCHEMBL22729587 | 0.70 | CCNE1 (0.33) | HPGD | |
| SCHEMBL5718827 | 0.64 | L3MBTL1 (0.58) | HCAR1ALDH1A1HPGDKDM4EPOLB | |
| SCHEMBL22729846 | 0.63 | KDM4E (0.43) | ATP4AATP4BGAAALDH1A1MGLL | |
| SCHEMBL3304455 | 0.63 | ALDH1A1 (0.54) | HCAR1GAAALDH1A1MGLLHPGD | |
| SCHEMBL8151089 | 0.62 | MAT2A (0.44) | HCAR1GAAALDH1A1MGLLHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11459325-B2 | Heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2022-10-04 | — | — | US | disclosed |
| US-20210087186-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-03-25 | — | — | US | disclosed |
| EP-3747885-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-12-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210087186-A1 | HETEROCYCLIC COMPOUND | GBA1, GBA2, GALC | ATP4A 1374/4885ATP4B 1763/4885HCAR1 2158/4885 |
| US-11459325-B2 | Heterocyclic compound | GBA1, GBA2, GALC | ATP4A 1511/4885ATP4B 1936/4885HCAR1 2077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.