SCHEMBL2273441

SCHEMBL2273441

C=C[Si](CCCC)(NC)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.34
NAAA Q02083 1/20 0.32
EGFR P00533 1/20 0.31
HTT P42858 2/20 0.31
TSHR P16473 2/20 0.31
EPHX1 P07099 3/20 0.30
ALDH1A1 P00352 2/20 0.30
EPHX2 P34913 1/20 0.30
POLB P06746 1/20 0.30
MAPT P10636 1/20 0.30
KCNH3 Q9ULD8 1/20 0.30
LMNA P02545 1/20 0.30
PAX8 Q06710 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2271394 0.87 SIGMAR1 (0.34) SIGMAR1NAAAEGFRHTTTSHR
SCHEMBL27943213 0.74 NR1H2 (0.33) SIGMAR1NAAAEGFRHTTTSHR
SCHEMBL2099682 0.73 NAAA (0.36) SIGMAR1NAAAHTTTSHREPHX1
SCHEMBL2270650 0.73 NAAA (0.36) SIGMAR1NAAAHTTTSHREPHX1
SCHEMBL2291148 0.72 PCSK9 (0.34) NAAAEGFRHTTTSHREPHX1
SCHEMBL15302895 0.72 NR1H2 (0.32) NAAATSHR
SCHEMBL2272329 0.72 THRA (0.33) SIGMAR1NAAATSHR
SCHEMBL8084574 0.70 KCNH2 (0.36) SIGMAR1NAAAEGFRHTTTSHR
SCHEMBL2101256 0.70 NAAA (0.34) SIGMAR1NAAAHTTTSHREPHX1
SCHEMBL3482101 0.70 LTA4H (0.33) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed