Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22747877 | 0.90 | KCNH2 (0.38) | KCNH2TAAR1DRD2HTR2A | |
| SCHEMBL22747872 | 0.79 | KCNH2 (0.40) | KCNH2TAAR1DRD2HTR2A | |
| SCHEMBL22747836 | 0.78 | EDNRA (0.36) | — | |
| SCHEMBL28556217 | 0.70 | ALDH1A1 (0.43) | — | |
| SCHEMBL22747835 | 0.70 | KMO (0.40) | — | |
| SCHEMBL22760495 | 0.68 | FOLH1 (0.37) | — | |
| SCHEMBL22748259 | 0.67 | NTRK1 (0.38) | — | |
| SCHEMBL22760079 | 0.67 | MAT2A (0.41) | HTR2ASLC6A4 | |
| SCHEMBL22747822 | 0.67 | GAA (0.38) | — | |
| SCHEMBL22760110 | 0.67 | VCP (0.36) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020244462-A1 | INDOLE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | 中国药科大学 | 2020-12-10 | — | — | WO | disclosed |
| CN-112028815-A | Indole derivatives and medical application thereof | 中国药科大学 | 2020-12-04 | — | — | CN | disclosed |