Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 2/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 4/20 | 0.33 |
| ▸ | CCR3 | P51677 | 4/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | THRA | P10827 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28558066 | 0.99 | VCP (0.37) | VCPFOLH1EDNRAPDE4DHRH1 | |
| SCHEMBL22748258 | 0.86 | NTRK1 (0.38) | FOLH1EDNRAPDE4DCCR2 | |
| SCHEMBL22748259 | 0.86 | NTRK1 (0.38) | FOLH1EDNRAPDE4DCCR2 | |
| SCHEMBL22760495 | 0.74 | FOLH1 (0.37) | FOLH1EDNRACCR2KMT2A | |
| SCHEMBL22747822 | 0.73 | GAA (0.38) | FOLH1EDNRAKMT2A | |
| SCHEMBL22760079 | 0.71 | MAT2A (0.41) | FOLH1EDNRATHRBCCR2 | |
| SCHEMBL22760364 | 0.69 | FOLH1 (0.37) | FOLH1EDNRACCR2KMT2A | |
| SCHEMBL22747835 | 0.69 | KMO (0.40) | EDNRAKMO | |
| SCHEMBL22747899 | 0.68 | HTR1A (0.40) | FOLH1EDNRA | |
| SCHEMBL22760097 | 0.68 | CHRM4 (0.45) | FOLH1HRH1CCR3KCNH2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020244462-A1 | INDOLE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | 中国药科大学 | 2020-12-10 | — | — | WO | disclosed |