SCHEMBL22749465

SCHEMBL22749465

CCN(CCO)CCN1CCOCC1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
KDM4E B2RXH2 1/20 0.50
SIGMAR1 Q99720 3/20 0.38
HPGD P15428 2/20 0.38
CYP1A2 P05177 2/20 0.38
MAPK1 P28482 2/20 0.38
GLA P06280 1/20 0.38
CYP2C9 P11712 1/20 0.38
HIF1A Q16665 1/20 0.38
HSD17B10 Q99714 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
KEAP1 Q14145 1/20 0.37
P2RY12 Q9H244 1/20 0.36
DUSP3 P51452 1/20 0.35
CHRM2 P08172 1/20 0.35
CHRM1 P11229 1/20 0.35
HTR2A P28223 1/20 0.35
SCN1A P35498 1/20 0.35
HTR2B P41595 1/20 0.35
KCNH2 Q12809 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27104595 0.94 ALDH1A1 (0.44) ALDH1A1KDM4ESIGMAR1HPGDCYP1A2
SCHEMBL13187933 0.89 KDM4E (0.57) ALDH1A1KDM4EHPGDGLAHSD17B10
SCHEMBL27220456 0.89 KDM4E (0.57) ALDH1A1KDM4EHPGDGLAHSD17B10
SCHEMBL10401216 0.87 ALDH1A1 (0.43) ALDH1A1KDM4ESIGMAR1HPGDCYP1A2
SCHEMBL23223379 0.85 SIGMAR1 (0.40) ALDH1A1KDM4ESIGMAR1CYP1A2MAPK1
SCHEMBL20628217 0.84 KDM4E (0.52) ALDH1A1KDM4EHPGDGLAHSD17B10
SCHEMBL18379164 0.83 SIGMAR1 (0.48) SIGMAR1HPGDCYP1A2MAPK1CYP2C9
SCHEMBL28502711 0.80 ALDH1A1 (0.38) ALDH1A1KDM4ESIGMAR1CYP1A2MAPK1
SCHEMBL1133412 0.79 KEAP1 (0.50) ALDH1A1KDM4ESIGMAR1HPGDCYP1A2
SCHEMBL1034010 0.78 KDM4E (0.50) ALDH1A1KDM4ESIGMAR1HPGDGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260102348-A1 COMPOUND OR SALT THEREOF AND LIPID PARTICLES FUJIFILM CORPORATION (JP) 2026-04-16 US disclosed
US-12508226-B2 Lipid composition FUJIFILM CORPORATION (JP) 2025-12-30 US disclosed
US-12370143-B2 Compound or salt thereof and lipid particles FUJIFILM CORPORATION (JP) 2025-07-29 US disclosed
EP-4328309-B1 LIPID COMPOSITION FUJIFILM CORP (JP) 2025-07-02 EP disclosed
US-12285525-B2 Compound or salt thereof and lipid particles FUJIFILM CORPORATION (JP) 2025-04-29 US disclosed
CN-116172975-B Lipid particle, nucleic acid drug comprising same, and composition for nucleic acid delivery 富士胶片株式会社 2025-03-28 CN disclosed
CN-114728016-B Lipid composition 富士胶片株式会社 2024-10-29 CN disclosed
US-20240315970-A1 COMPOUND OR SALT THEREOF AND LIPID PARTICLES FUJIFILM CORPORATION (JP) 2024-09-26 US disclosed
CN-113924128-B Lipid composition 富士胶片株式会社 2024-09-06 CN disclosed
EP-4328309-A2 LIPID COMPOSITION FUJIFILM Corporation (JP) 2024-02-28 EP disclosed
CN-114728016-A Lipid composition 富士胶片株式会社 2022-07-08 CN disclosed
EP-3981435-A1 LIPID COMPOSITION FUJIFILM Corporation (JP) 2022-04-13 EP disclosed
US-20220096381-A1 LIPID COMPOSITION FUJIFILM CORPORATION (JP) 2022-03-31 US disclosed
CN-113924128-A Lipid composition 富士胶片株式会社 2022-01-11 CN disclosed
WO-2021095876-A1 LIPID COMPOSITION 富士フイルム株式会社 2021-05-20 WO disclosed
EP-3805198-A1 COMPOUND, SALT THEREOF AND LIPID PARTICLES FUJIFILM Corporation (JP) 2021-04-14 EP disclosed
US-20210085604-A1 COMPOUND OR SALT THEREOF AND LIPID PARTICLES FUJIFILM CORPORATION (JP) 2021-03-25 US disclosed
US-20210085604-A1 COMPOUND OR SALT THEREOF AND LIPID PARTICLES FUJIFILM CORPORATION (JP) 2021-03-25 US disclosed
CN-112262122-A Compound or salt thereof, and lipid particle 富士胶片株式会社 2021-01-22 CN disclosed
WO-2020246581-A1 LIPID COMPOSITION 富士フイルム株式会社 2020-12-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12370143-B2 Compound or salt thereof and lipid particles NR1H3, NR1H2, LDLR ALDH1A1 2243/4885KDM4E 3138/4885SIGMAR1 24/4885
US-12285525-B2 Compound or salt thereof and lipid particles NR1H3, NR1H2, LDLR ALDH1A1 2243/4885KDM4E 3138/4885SIGMAR1 24/4885
US-20240315970-A1 COMPOUND OR SALT THEREOF AND LIPID PARTICLES NR1H3, NR1H2, LDLR ALDH1A1 2243/4885KDM4E 3138/4885SIGMAR1 24/4885
US-20260102348-A1 COMPOUND OR SALT THEREOF AND LIPID PARTICLES LDLR, NR1H3, NR1H2 ALDH1A1 2418/4885KDM4E 3995/4885SIGMAR1 52/4885
US-20210085604-A1 COMPOUND OR SALT THEREOF AND LIPID PARTICLES NR1H3, NR1H2, LDLR ALDH1A1 2368/4885KDM4E 3119/4885SIGMAR1 25/4885
US-20220096381-A1 LIPID COMPOSITION NR1H3, NR1H4, NR1H2 ALDH1A1 3097/4885KDM4E 3538/4885SIGMAR1 26/4885
US-12508226-B2 Lipid composition APOB, NAF1, SLC27A1 ALDH1A1 2907/4885KDM4E 3879/4885SIGMAR1 240/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.