Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 2/20 | 0.41 |
| ▸ | TAF1 | P21675 | 9/20 | 0.39 |
| ▸ | CECR2 | Q9BXF3 | 9/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 7/20 | 0.39 |
| ▸ | BRD4 | O60885 | 3/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 3/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.34 |
| ▸ | FPR1 | P21462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22755067 | 0.80 | MDM4 (0.46) | NPY5RJAK1 | |
| SCHEMBL17754002 | 0.71 | TAF1 (0.77) | TAF1CECR2BRD9BRD4 | |
| SCHEMBL22755241 | 0.70 | AVPR1A (0.51) | HPGDTSHR | |
| SCHEMBL19658738 | 0.69 | NPY5R (0.56) | NPY5R | |
| SCHEMBL22754863 | 0.69 | CYP2C9 (0.54) | — | |
| SCHEMBL22755246 | 0.68 | CYP2C9 (0.61) | — | |
| SCHEMBL22754859 | 0.68 | SPR (0.45) | HPGDTSHR | |
| SCHEMBL22755346 | 0.67 | CNR2 (0.39) | HPGDTSHRJAK1JAK2 | |
| SCHEMBL22754851 | 0.67 | RAB9A (0.52) | — | |
| SCHEMBL19652129 | 0.66 | NPY5R (0.53) | NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3747885-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2020-12-09 | — | — | EP | disclosed |