SCHEMBL2275568

SCHEMBL2275568

CCC[Si](NC)(c1ccccc1)C(C)C

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.34
SIGMAR1 Q99720 3/20 0.34
SLC18A2 Q05940 1/20 0.34
BRD4 O60885 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
KMT2A Q03164 2/20 0.31
MEN1 O00255 1/20 0.31
HTR2A P28223 1/20 0.31
HRH1 P35367 1/20 0.31
TDP1 Q9NUW8 1/20 0.30
POLB P06746 2/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2268318 0.85 SIGMAR1 (0.36) TAAR1SIGMAR1SLC18A2BRD4SMN1; SMN2
SCHEMBL2272184 0.74 KMT2A (0.32) TAAR1KMT2ATDP1POLBALDH1A1
SCHEMBL2101644 0.74 NR1H2 (0.32) TAAR1KMT2AALDH1A1MAPT
SCHEMBL20499846 0.72 ESR1 (0.33) TAAR1KMT2AALDH1A1MAPT
Dimethylamine SCHEMBL8199596 0.71 ESR1 (0.41) TAAR1SMN1; SMN2KMT2AALDH1A1MAPT
SCHEMBL2272188 0.71 KMT2A (0.31) KMT2AMAPT
SCHEMBL2271815 0.71 SMN1; SMN2 (0.32) SIGMAR1SMN1; SMN2POLB
SCHEMBL2102178 0.71 MAPT (0.31) SMN1; SMN2KMT2AALDH1A1MAPT
SCHEMBL703034 0.69 TSHR (0.31) SIGMAR1KMT2A
SCHEMBL2099888 0.69 TDP1 (0.36) TAAR1SIGMAR1SLC18A2KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed