SCHEMBL2268318

SCHEMBL2268318

CCC[Si](NCC)(c1ccccc1)C(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 4/20 0.36
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
HPGD P15428 1/20 0.32
HTT P42858 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
KCNN4 O15554 1/20 0.31
BRD4 O60885 1/20 0.31
MTNR1A P48039 1/20 0.31
MTNR1B P49286 1/20 0.31
TAAR1 Q96RJ0 3/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
LMNA P02545 1/20 0.31
CACNA1F O60840 1/20 0.31
CHRM2 P08172 1/20 0.31
CHRM1 P11229 1/20 0.31
ADRA2B P18089 1/20 0.31
CHRM3 P20309 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2275568 0.85 TAAR1 (0.34) SIGMAR1ALDH1A1SMN1; SMN2BRD4TAAR1
SCHEMBL2104720 0.74 SIGMAR1 (0.39) SIGMAR1KDM4EALDH1A1GAAHPGD
SCHEMBL2269102 0.74 SIGMAR1 (0.39) SIGMAR1KDM4EALDH1A1GAAHPGD
SCHEMBL2272798 0.74 GAA (0.35) SIGMAR1KDM4EALDH1A1GAAHPGD
SCHEMBL2102969 0.74 GAA (0.35) SIGMAR1KDM4EALDH1A1GAAHPGD
SCHEMBL2102370 0.71 SIGMAR1 (0.37) SIGMAR1ALDH1A1HTTSMN1; SMN2KCNN4
SCHEMBL2103213 0.71 GAA (0.34) KDM4EALDH1A1GAAHPGDHTT
SCHEMBL2271815 0.71 SMN1; SMN2 (0.32) SIGMAR1SMN1; SMN2
SCHEMBL2269776 0.71 GAA (0.33) KDM4EALDH1A1GAAHPGDSMN1; SMN2
SCHEMBL2273250 0.70 ESR1 (0.38) SIGMAR1KDM4EALDH1A1GAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed