Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.37 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.37 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.37 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.37 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.37 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 3/20 | 0.36 |
| ▸ | NT5E | P21589 | 3/20 | 0.33 |
| ▸ | HINT1 | P49773 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22757335 | 0.82 | ALDH1A1 (0.68) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL7069026 | 0.81 | PRKAB2 (0.46) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL8284676 | 0.80 | LMNA (0.56) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL18759054 | 0.79 | HINT1 (0.54) | ALDH1A1NT5EHINT1 | |
| SCHEMBL7257443 | 0.79 | HINT1 (0.54) | ALDH1A1NT5EHINT1 | |
| SCHEMBL23982314 | 0.78 | HSP90B1 (0.52) | ADORA3 | |
| SCHEMBL9657596 | 0.78 | HSP90B1 (0.52) | ADORA3 | |
| SCHEMBL7054416 | 0.78 | ALDH1A1 (0.52) | ALDH1A1LMNATP53MAPTTDP1 | |
| SCHEMBL30561564 | 0.78 | HSP90B1 (0.52) | ADORA3 | |
| SCHEMBL20419139 | 0.78 | HSP90B1 (0.52) | ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020247546-A1 | ADENOSINE ANALOGS FOR THE TREATMENT OF DISEASE | BIOINTERVENE, INC. (US) | 2020-12-10 | — | — | WO | disclosed |