SCHEMBL22758448

SCHEMBL22758448

CC(C)c1cc2ccc(CC(C)c3cccs3)cc2s1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
HTR2B P41595 1/20 0.35
CYP3A4 P08684 3/20 0.33
CYP2D6 P10635 3/20 0.33
SLC6A2 P23975 3/20 0.33
SLC6A4 P31645 3/20 0.33
SLC6A3 Q01959 3/20 0.33
KCNH2 Q12809 3/20 0.33
CASP3 P42574 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
SIGMAR1 Q99720 1/20 0.31
ALDH1A1 P00352 1/20 0.30
POLB P06746 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
EGFR P00533 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14260571 0.79 GABRA1 (0.40) HTR2AHTR2CHTR2BSIGMAR1POLB
SCHEMBL24835508 0.79 CYP2A6 (0.39) HTR2AHTR2CHTR2BSIGMAR1ALDH1A1
SCHEMBL22374289 0.74 LOXL2 (0.52) HTR2AHTR2CHTR2BALDH1A1MAPT
SCHEMBL20713611 0.69 HDAC3 (0.46) HTR2BSLC6A2MAPT
SCHEMBL20444413 0.69 AHR (0.35)
SCHEMBL21976903 0.69 ALOX5 (0.36) HTR2AHTR2CHTR2B
SCHEMBL17480203 0.68 PRMT6 (0.42) CYP3A4CYP2D6SLC6A2SLC6A4SLC6A3
SCHEMBL17480206 0.68 SMN1; SMN2 (0.37) CYP3A4CYP2D6TAAR1SIGMAR1ALDH1A1
SCHEMBL24519226 0.67 GABRA1 (0.40) HTR2AHTR2CHTR2BSIGMAR1POLB
SCHEMBL24386803 0.67 HTR2A (0.38) HTR2AHTR2CHTR2BSIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11152578-B2 Sulfonium salts of DNTT and related compounds as soluble photocleavable precursors for organic semiconductors for use in organic field-effect transistors CLAP CO., LTD. (KR) 2021-10-19 US disclosed
US-20200388772-A1 SULFONIUM SALTS OF DNTT AND RELATED COMPOUNDS AS SOLUBLE PHOTOCLEAVABLE PRECURSORS FOR ORGANIC SEMICONDUCTORS FOR USE IN ORGANIC FIELD-EFFECT TRANSISTORS CLAP CO., LTD. (KR) 2020-12-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200388772-A1 SULFONIUM SALTS OF DNTT AND RELATED COMPOUNDS AS SOLUBLE PHOTOCLEAVABLE PRECURSORS FOR ORGANIC SEMICONDUCTORS FOR USE IN ORGANIC FIELD-EFFECT TRANSISTORS DNTT, TST, SULT1A1 HTR2A 4490/4885HTR2C 4267/4885HTR2B 3767/4885
US-11152578-B2 Sulfonium salts of DNTT and related compounds as soluble photocleavable precursors for organic semiconductors for use in organic field-effect transistors DNTT, TST, SULT1A1 HTR2A 4490/4885HTR2C 4267/4885HTR2B 3767/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.