Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.35 |
| ▸ | TOP2A | P11388 | 2/20 | 0.35 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22760197 | 0.88 | MAPT (0.42) | HTR1ASLC6A2SLC6A4SLC6A3SUCNR1 | |
| SCHEMBL22760097 | 0.81 | CHRM4 (0.45) | SLC6A2SLC6A4SLC6A3HTR2CHTR2B | |
| SCHEMBL22760191 | 0.75 | MAPK8 (0.46) | — | |
| SCHEMBL22747874 | 0.71 | MAPT (0.43) | HTR2CHTR2BUTS2R | |
| SCHEMBL22760096 | 0.69 | REN (0.39) | HTR1ASLC6A2SLC6A4SLC6A3REN | |
| SCHEMBL22760110 | 0.68 | VCP (0.36) | FOLH1EDNRA | |
| SCHEMBL22747915 | 0.66 | ALDH1A1 (0.40) | RENFOLH1EDNRA | |
| SCHEMBL22747863 | 0.65 | MAT2A (0.47) | EDNRA | |
| SCHEMBL22747852 | 0.65 | EDNRA (0.40) | FOLH1EDNRA | |
| SCHEMBL28912331 | 0.64 | FOLH1 (0.37) | RENFOLH1EDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020244462-A1 | INDOLE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | 中国药科大学 | 2020-12-10 | — | — | WO | disclosed |
| WO-2020244462-A1 | INDOLE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | 中国药科大学 | 2020-12-10 | — | — | WO | disclosed |