Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2271442 | 0.89 | TSHR (0.46) | TSHRLMNAALDH1A1GRM2KMT2A | |
| SCHEMBL29582311 | 0.88 | NPC1 (0.44) | TSHRLMNAALDH1A1CYP1A2SMN1; SMN2 | |
| SCHEMBL1268914 | 0.88 | NPC1 (0.44) | TSHRLMNAALDH1A1CYP1A2SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL7212028 | 0.86 | NPC1 (0.43) | TSHRLMNAALDH1A1CYP1A2SMN1; SMN2 | |
| SCHEMBL2268679 | 0.79 | LMNA (0.44) | TSHRLMNAALDH1A1CYP1A2SMN1; SMN2 | |
| SCHEMBL29379587 | 0.78 | CYP2C19 (0.56) | TSHRLMNAALDH1A1CYP1A2NPC1 | |
| SCHEMBL6803 | 0.78 | CYP2C19 (0.56) | TSHRLMNAALDH1A1CYP1A2NPC1 | |
| SCHEMBL5517724 | 0.77 | LMNA (0.50) | TSHRLMNAALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL423447 | 0.77 | CYP2D6 (0.50) | TSHRLMNACYP1A2SMN1; SMN2NPC1 | |
| SCHEMBL5515476 | 0.76 | LTB4R (0.54) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8003688-B2 | Method of treating symptoms of common cold, allergic rhinitis and infections relating to the respiratory tract | IMMUPHARM APS (DK) | 2011-08-23 | — | — | US | disclosed |
| US-7671086-B2 | Pharmaceutical compositions comprising flavonoids and menthol | IMMUPHARM A/S (DK) | 2010-03-02 | — | — | US | disclosed |
| US-20090227670-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING FLAVONOIDS AND MENTHOL | IMMUPHARM A/S (DK) | 2009-09-10 | — | — | US | disclosed |
| US-7585890-B2 | Pharmaceutical compositions comprising flavonoids and menthol | IMMUNPHARM A/S (DK) | 2009-09-08 | — | — | US | disclosed |
| EP-2089422-A1 | METHODS OF SEPARATING NUCLEIC ACIDS AND PROTEIN | Natimmune A/S (DK) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008106979-A2 | PHARMACEUTICAL COMPOSITIONS COMPRISING FLAVONOIDS AND XYLITOL | IMMUPHARM A/S (DK) | 2008-09-12 | — | — | WO | disclosed |
| WO-2008064686-A1 | METHODS OF SEPARATING NUCLEIC ACIDS AND PROTEIN | NATIMMUNE A/S (DK) | 2008-06-05 | — | — | WO | disclosed |
| EP-1556021-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING FLAVONOIDS AND MENTHOL | IMMUPHARM AS (DK) | 2007-12-19 | — | — | EP | disclosed |
| US-7166640-B2 | Method of treating symptoms of common cold, allergic rhinitis and infections relating to the respiratory tract | IMMUPHARM APS (DK) | 2007-01-23 | — | — | US | disclosed |
| US-20060148726-A1 | Pharmaceutical compositions comprising flavonoids and menthol | IMMUPHARM A/S C/O NOVI A/S, NIELS JERNES VEJ 10 (DK) | 2006-07-06 | — | — | US | disclosed |
| EP-1307189-B1 | USE OF HYDROXYETHYLRUTOSIDES FOR TREATING SYMPTOMS OF COMMON COLD, ALLERGIC RHINITIS AND INFECTIONS RELATING TO THE RESPIRATORY TRACT | IMMUPHARM APS (DK) | 2006-05-10 | — | — | EP | disclosed |
| US-20050245467-A1 | Method of treating symptoms of common cold, allergic rhinitis and infections relating to the respiratory tract | IMMUPHARM APS (DK) | 2005-11-03 | — | — | US | disclosed |
| EP-1556021-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING FLAVONOIDS AND MENTHOL | Immupharm A/S (DK) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004037237-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING FLAVONOIDS AND MENTHOL | IMMUPHARM A/S (DK) | 2004-05-06 | — | — | WO | disclosed |
| US-20040053858-A1 | Method of treating symptoms of common cold, allergic rhinitis and infections relating to the respiratory tract | IMMUPHARM APS (DK) | 2004-03-18 | — | — | US | disclosed |
| EP-1307189-A2 | METHOD OF TREATING SYMPTOMS OF COMMON COLD, ALLERGIC RHINITIS AND INFECTIONS RELATING TO THE RESPIRATORY TRACT | Immupharm APS (DK) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002009699-A2 | METHOD OF TREATING SYMPTOMS OF COMMON COLD, ALLERGIC RHINITIS AND INFECTIONS RELATING TO THE RESPIRATORY TRACT | IMMUPHARM APS (DK) | 2002-02-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148726-A1 | Pharmaceutical compositions comprising flavonoids and menthol | CHIA, MAVS, C1QBP | TSHR 4733/4885LMNA 2370/4885ALDH1A1 1674/4885 |
| US-20050245467-A1 | Method of treating symptoms of common cold, allergic rhinitis and infections relating to the respiratory tract | CMA1, CHIA, C1QBP | TSHR 3718/4885LMNA 4008/4885ALDH1A1 1900/4885 |
| US-20040053858-A1 | Method of treating symptoms of common cold, allergic rhinitis and infections relating to the respiratory tract | CMA1, CHIA, C1QBP | TSHR 3718/4885LMNA 4008/4885ALDH1A1 1900/4885 |
| US-20090227670-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING FLAVONOIDS AND MENTHOL | CHIA, MAVS, C1QBP | TSHR 4733/4885LMNA 2370/4885ALDH1A1 1674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.