Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 10/20 | 0.66 |
| ▸ | HTT | P42858 | 3/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.66 |
| ▸ | SLC40A1 | Q9NP59 | 9/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.65 |
| ▸ | MITF | O75030 | 1/20 | 0.65 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.65 |
| ▸ | CKS1B | P61024 | 1/20 | 0.65 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.65 |
| ▸ | NFKBIA | P25963 | 2/20 | 0.62 |
| ▸ | G6PD | P11413 | 1/20 | 0.62 |
| ▸ | METAP2 | P50579 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13485950 | 0.81 | SLC40A1 (0.80) | GLO1HTTALOX15SLC40A1TDP1 | |
| SCHEMBL6862410 | 0.81 | GLO1 (1.00) | GLO1HTTALOX15SLC40A1TDP1 | |
| SCHEMBL29941063 | 0.81 | GLO1 (1.00) | GLO1HTTALOX15SLC40A1TDP1 | |
| SCHEMBL13485924 | 0.80 | GLO1 (0.84) | GLO1HTTALOX15SLC40A1TDP1 | |
| SCHEMBL4471796 | 0.79 | TDP1 (1.00) | GLO1HTTSLC40A1TDP1KMT2A | |
| SCHEMBL13485929 | 0.78 | SLC40A1 (0.92) | GLO1HTTALOX15SLC40A1TDP1 | |
| SCHEMBL15299831 | 0.78 | TDP1 (0.97) | GLO1HTTSLC40A1TDP1KMT2A | |
| SCHEMBL2337402 | 0.78 | TDP1 (0.97) | GLO1HTTSLC40A1TDP1KMT2A | |
| SCHEMBL5572103 | 0.78 | TDP1 (0.97) | GLO1HTTSLC40A1TDP1KMT2A | |
| SCHEMBL30925450 | 0.78 | SLC40A1 (0.70) | GLO1HTTSLC40A1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11691949-B2 | Quinoline sulfonamide compounds and their use as antibacterial agents | OTAGO INNOVATION LIMITED (NZ) | 2023-07-04 | — | — | US | disclosed |
| US-20200385354-A1 | Quinoline Sulfonamide Compounds and Their Use as Antibacterial Agents | OTAGO INNOVATION LIMITED (NZ) | 2020-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11691949-B2 | Quinoline sulfonamide compounds and their use as antibacterial agents | NQO2, SDHA, SIRT5 | GLO1 369/4885HTT 3885/4885ALOX15 4586/4885 |
| US-20200385354-A1 | Quinoline Sulfonamide Compounds and Their Use as Antibacterial Agents | NQO2, SDHA, SIRT5 | GLO1 369/4885HTT 3885/4885ALOX15 4586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.